Publications by authors named "Sium Wolde Sellasie"
The measurement of Calcitonin (Ctn) in fine-needle aspiration (FNA) washout fluids (FNA-Ctn) has demonstrated excellent sensitivity, significantly higher than FNA cytology, in detecting medullary thyroid carcinoma (MTC). However, the absence of a fixed cutoff value for FNA-Ctn poses a limitation. This study aimed to investigate whether the sensitivity of FNA-Ctn in detecting MTC varies with different cutoffs reported in the literature.
View Article and Find Full Text PDFThyroid Hormone Resistance: A 17-Year Follow-up Case Report.
Endocr Metab Immune Disord Drug Targets
August 2024
Background: Resistance to thyroid hormone is a rare syndrome characterized by peripheral resistance to thyroid hormones. It is caused by genetic dysfunction of thyroid receptor genes, with Thyroid hormone Receptor-beta (TRβ) being the most prevalent. Affected patients show high thyroid hormone levels and non-suppressed Thyroid-stimulating Hormone (TSH).
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- * A 63-year-old man with post-surgical hypoparathyroidism was hospitalized for a complication related to his cardiac device, during which he experienced severe hypocalcemia and critical heart changes due to poorly managed therapy.
- * Consistent and precise long-term treatment with calcium and calcitriol is crucial for maintaining health in hypoparathyroid patients, especially when they have other health problems or face acute medical situations.
Article Synopsis
- - The study examines the prevalence of diabetes mellitus (DM) among patients with osteoporosis and fragility fractures, finding a prevalence rate of 12.7% among the 589 patients analyzed.
- - Patients with DM exhibited more combinations of vertebral and hip fractures and had a higher proportion of males, but their bone mineral density (BMD) was higher compared to those without DM.
- - Interestingly, while BMD was better in the DM group, their trabecular bone score (TBS) was significantly lower, suggesting that TBS may serve as a more reliable indicator of bone health in these patients than BMD.
The incidence of papillary thyroid carcinoma (PTC) is increasing and PTC ≤ 10 mm (PTMC) accounts for most new diagnoses. PTMCs are not always low risk, as detection of lymph nodes metastasis (LNM) may occur. The purpose of the study was to analyze the clinical pattern, frequency, and independent risk factors of patients with PTMC and LNM.
View Article and Find Full Text PDFBackground: The purpose of this study is to access whether a personal attitude to physical activity (PA) may influence the appearance of diabetic polyneuropathy (DPN) patients with well-controlled type 1 diabetes mellitus.
Methods: Ninety patients attending the diabetes technology outpatient clinic were enrolled. DPN was investigated according to the Toronto consensus diagnostic criteria.
Article Synopsis
- Several risk stratification score systems for evaluating thyroid nodules exist, and this study aimed to assess the effectiveness of the American College of Radiology TI-RADS in distinguishing malignancy among nodules.
- The research involved 830 nodules, with a significant percentage of those categorized as suspicious (TIR3B/TIR4/TIR5) ultimately proving to be cancerous after surgery.
- The results suggest that the ACR TI-RADS guidelines for fine needle aspiration cytology (FNAC) may need to be updated, particularly to include more cases classified as TR4 nodules for further evaluation.