Publications by authors named "Siu-Yi Leung"
Article Synopsis
- The study explored the effects of a probiotic strain, BC198, and its heat-killed version on colitis caused by dextran sulfate sodium, focusing on their ability to improve gut health.
- Both forms of BC198 improved gut barrier function and reduced harmful immune responses, but only the live strain effectively alleviated colitis symptoms and prevented colon damage.
- At the molecular level, live BC198 worked by inhibiting pro-inflammatory cells while promoting beneficial anti-inflammatory responses, showcasing its superior effectiveness compared to the heat-killed form.
Fibroblast growth factor 2 (FGF-2) and glial cell line-derived neurotrophic factor (GDNF) support survival of dopaminergic midbrain neurons. Neurons are coupled by gap junctions, propagating metabolites and intracellular second messengers possibly mediating growth factor effects. We asked, therefore, whether gap junctions influence the survival-promoting effects of FGF-2 and GDNF.
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