Hybridogenesis in the Water Frogs from Western Russian Territory: Intrapopulation Variation in Genome Elimination.

Hybridogenesis in an interspecific hybrid frog is a coupling mechanism in the gametogenic cell line that eliminates the genome of one parental species with endoduplication of the remaining genome of the other parental species. It has been intensively investigated in the edible frog (RL) a natural hybrid between the marsh frog (RR) and the pool frog (LL). However, the genetic mechanisms involved remain unclear.

[Treatment of ARVI and influenza in patients with arterial hypertension].

Aim: to study the flow phenomena of influenza and ARVI in patients with arterial hypertension, as well as the effectiveness of antiviral therapy.

Materials And Methods: Analyzed data was collected during the international multicenter prospective observational FLU-EE study "Treatment of ARVI and influenza in routine clinical practice". The study included 18946 patients with established diagnosis of influenza or ARVI of varying severity.

[Treatment of influenza and other acute respiratory viral infections in patients with diabetes mellitus].

Purpose Of The Study: The study of the influenza and ARVI clinical performance, the development of patients with diabetes mellitus, evaluation of the effectiveness and safety application of antiviral therapy, carried out in the framework of routine clinical practice.

Materials And Methods: 126 patients aged from 22 to 83 years (27.8% of men) with ARVI or influenza that occurred with medical care during the first 5 days of the disease (60.

Current Strategies in Prevention of Postoperative Infections in Spine Surgery.

Study Design: Narrative review.

Objectives: Postoperative surgical site infections (SSIs) are among the most common acute complications in spine surgery and have a devastating impact on outcomes. They can lead to increased morbidity and mortality as well as greater economic burden.

[Treatment for acute respiratory viral infection and influenza in daily clinical practice: Results of the multicenter international observational FLU-EE study].

Purpose: To study the clinical aspects of influenza and acute respiratory viral infection (ARVI) in routine clinical practice, with efficacy and safety of the antiviral therapy evaluation.

Subjects And Methods: In the large multicenter prospective observational study were enrolled 18,946 patients aged 18 to 93 years with previously determined diagnosis of influenza or ARVI from 262 outpatient sites in Russia, Armenia, Moldova and Georgia. According to study design, 3 visits were evaluated.

Retention of Skills After Simulation-based Training in Orthopaedic Surgery.

Simulation-based surgical skills training has become essential in orthopaedic practice because of concerns about patient safety and an increase in technically challenging procedures. Surgical skills training in specifically designed simulation laboratories allows practice of procedures in a risk-free environment before they are performed in the operating room. The transferability of acquired skills to performance with patients is the most effective measure of the predictive validity of simulation-based training.

The Effect of Antiviral Therapy on the Incidence of Bacterial Aggravations and Administration of Systemic Antibiotics in Patients with Acute Respiratory Viral Infections and Influenza (Results of International Cohort Observational Study).

Objective: to evaluate the incidence of bacterial aggravations and antibiotics administration with analysis of effectiveness of antiviral therapy in ambulatory patients with acute viral respiratory infection (ARVI) and influenza.

Material And Methods: International cohort open non-interventional .study < View Article and Find Full Text PDF

[Optimization of hepatoprotective therapy of viral hepatitis with consideration of neuromediatory link of pathogenesis].

Aim: To study therapeutic efficacy of hepatoprotective modalities on the experimental hepatitis model and in patients with parenteral hepatitis B and C regarding neurogenic amines and their coefficients.

Material And Methods: 38 hepatoprotectors were screened for the highest activity in 1000 white rats with toxic hepatitis. Blood catecholamines (CA), histamine (H), serotonin (S), 11-oxycorticosteroids (11-OCS) were studied in 100 patients with acute hepatitis B and C.