Publications by authors named "Sitheswaran Nainamalai"
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Synopsis of recent research by authors named "Sitheswaran Nainamalai"
- Sitheswaran Nainamalai's research primarily focuses on developing innovative therapeutic strategies for skin diseases, particularly employing RNA interference techniques for targeted gene silencing through non-invasive administration of siRNAs.
- His studies include generating a novel reporter mouse model to evaluate the efficacy of topical siRNA formulations in vivo, highlighting the challenges associated with delivering large macromolecules across the skin barrier.
- Additionally, Nainamalai has explored the roles of the nuclear receptor PPARδ in vital physiological processes and its potential implications in metabolism and tumor biology, demonstrating significant effects on body weight in transgenic mouse models.
