Haemostatic and cytokine changes in gestational diabetes mellitus.

Background: Limited data indicate the existence of a hypercoagulable state and the possible involvement of pro-inflammatory cytokines in the pathogenesis of gestational diabetes mellitus (GDM).

Aim: To characterise the coagulation inhibitor and cytokine profiles in women with GDM.

Methods: Two groups of women in the third trimester of pregnancy were studied: GDM (n = 150) and controls: women with normal pregnancy (n = 100); GDM in their first post-delivery day (n = 52).