Benzaldehyde and azaphilone derivatives from the marine-derived fungus PSU-AMF89.

Two new compounds including one benzaldehyde () and one azaphilone () were isolated from the marine-derived fungus PSU-AMF89 together with nine known compounds (-). Their structures were determined by spectroscopic evidences. The absolute configuration of was established by comparison of the ECD data with those of the previously reported data of compound as well as the biosynthetic consideration.

Penicitrisochromans A-C, new isochromans from the marine-derived fungus PSU-MF100.

Three new isochroman derivatives, penicitrisochromans A-C (-), together with 25 known polyketides were isolated from the marine-derived fungus PSU-MF100. Their structures were elucidated by extensive spectroscopic analysis. The absolute configurations of and were established by comparison of specific rotations and electronic circular dichroism (ECD) data with those of the known co-metabolite whereas those of were assigned based on the ECD calculation and biosynthetic consideration.

Unravelling the hidden diversity of cave mycobiota in Thailand's Satun Geopark.

Karst caves are distinctive ecosystems that have limited nutrients, darkness, low to moderate temperatures, and high moisture levels, which allow for a diverse range of fungal communities to thrive. Despite their significance, little is understood about the fungi found in karst caves in Thailand. In 2019, we studied the cultured mycobiota from five substrate types (air, water, rock, soil/sediment, and organic debris) in two karst caves (Le Stegodon and Phu Pha Phet Caves) of the Satun UNESCO Global Geopark, southern Thailand.

Contaminated fungi in dried salted fishes: Isolation, identification, and their inhibition by chitooligosaccharide-gallic acid conjugate.

Contaminated fungi on dried salted fish of three species including Talang queenfish (TQF, Scomberroides commersonianus), Hamilton's thryssa fish (HTF, Thryssa hamiltonii), and Cobia fish (CF, Rachycentron canadum) were isolated and identified. One hundred and sixty-nine isolates were obtained from TQF and HTF, respectively, while no fungi were detected in CF. The dominant genera were Aspergillus spp.

Talarostatin, a vermistatin derivative from the soil-derived fungus PSU-SPSF059.

The soil-derived fungus PSU-SPSF059 produced one new vermistatin derivative, talarostatin, and seven known compounds including two vermistatins, two chrodrimanins, two diphenyl ethers and one penicillide derivative. Extensive spectroscopic analysis was performed to identify their structures. The absolute configuration of talarostatin was determined by comparing the experimental and calculated electronic circular dichroism data.

Two Novel Species of Discovered in a Karst Cave in the Satun UNESCO Global Geopark of Southern Thailand.

Karst caves are oligotrophic environments that appear to support a high diversity of fungi. Studies of fungi in Thailand's caves are limited. During a 2019 exploration of the mycobiota associated with soil samples from a karst cave, namely, Phu Pha Phet in the Satun UNESCO Global Geopark in Satun Province, southern Thailand, two previously undescribed fungi belonging to (, , ) were studied using a polyphasic approach combining phenotypic and molecular data.

Furanone, morpholinone and tetrahydrofuran derivatives from the marine-derived fungus sp. PSU-MF07.

Three new compounds including one furanone, one morpholinone and one tetrahydrofuran together with three known compounds were isolated from the broth extract of the marine-derived fungus sp. PSU-MF07. The structures of the isolated compounds were determined on the basis of spectroscopic methods.

Sesquiterpenes from the soil-derived fungus PSU-SPSF346.

Two new sesquiterpenes, trichocitrinovirenes A () and B (), and five known compounds including four structurally related sesquiterpenes and one γ-lactone were isolated from the soil-derived fungus PSU-SPSF346. The structures were identified by analysis of their spectroscopic data. The relative configuration was assigned based on NOEDIFF data.

A nonadride derivative from the marine-derived fungus PSU-AMF79.

One new nonadride enantiomer, -epiheveadride, along with five known dioxopiperazine derivatives were isolated from the marine-derived fungus PSU-AMF79. Their structures were identified by extensive spectroscopic analysis. The absolute configuration of -epiheveadride was determined by comparison of the specific rotation and electronic circular dichroism data with those of related known compounds.

-Pyrone and decalin derivatives from the marine-derived fungus PSU-MF79.

Two new compounds, one -pyrone (trichoharzianone) and one decalin (trichoharzianin), along with eight known compounds including three decalins, two -lactones, two carboxylic acids and one isochroman were isolated from the marine-derived fungus PSU-MF79. The structures were determined by spectroscopic methods. The relative configuration of trichoharzianin was assigned based on NOEDIFF data and coupling constants whereas the absolute configurations were established by comparison of electronic circular dichroism data with those of the co-metabolites.

Two new farnesyl hydroquinones from (BCC 35283), the fungus associated with algae.

Two new hydroquinones bearing a 1,3-enyne moiety, pestalotioquinols G and H, together with four known compounds, including pestalotioquinol A, phomonitroester, ()-4,6,8-trihydroxy-3,4-dihydronaphthalen-1(2)-one, and scylatone were isolated from the marine fungus (BCC 35283). The structures of these compounds were elucidated by analysis of 2D-NMR and HR-MS data. The known pestalotioquinol A displayed antimalarial activity against K1 with an IC value of 19.

2-Oxaspiro[4.5]decane and -pyrenocine derivatives from the endophytic fungus sp. PSU-H51.

One new 2-oxaspiro[4.5]decane, roussoellide, and one new pyrenocine, 2,3-dihydropyrenocine A, together with nine known compounds including known arthropsolide A, and pyrenocines A and E, were obtained from the culture broth of the endophytic fungus sp. Their structures were determined using spectroscopic data.

Depsidones and a dihydroxanthenone from the endophytic fungi Simplicillium lanosoniveum (J.F.H. Beyma) Zare & W. Gams PSU-H168 and PSU-H261.

Three new compounds including two depsidones (simplicildones J and K) and one dihydroxanthenone (globosuxanthone E) together with nine known compounds were obtained from the crude extracts of two endophytic fungi Simplicillium lanosoniveum (J.F.H.

Depsidones and an α-pyrone derivative from Simplicillium sp. PSU-H41, an endophytic fungus from Hevea brasiliensis leaf [corrected].

Nine previously undescribed depsidones (simplicildones A-I) and one previously undescribed α-pyrone (simplicilopyrone) were isolated from the endophytic fungus Simplicillium sp. PSU-H41 along with 11 known compounds. Their structures were established by extensive spectroscopic analysis.

γ-Butenolide and furanone derivatives from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178.

Chromatographic separation of the broth extract of the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 resulted in isolation of four γ-butenolide-furanone dimers, aspersclerotiorones A-D, a furanone derivative, aspersclerotiorone E, and two γ-butenolide derivatives, aspersclerotiorones F and G, together with six known compounds, penicillic acid, dihydropenicillic acid, 5,6-dihydro-6-hydroxypenicillic acid, 6-methoxy-5,6-dihydropenicillic acid, coculnol and (4R,5R)-4,5-dihydroxy-3-methoxy-5-methylcyclohex-2-en-1-one. Their structures were determined by spectroscopic evidence. For aspersclerotiorones A and B, the structures were confirmed by single-crystal X-ray diffraction crystallography.

Flavodonfuran: a new difuranylmethane derivative from the mangrove endophytic fungus Flavodon flavus PSU-MA201.

One new difuranylmethane derivative, flavodonfuran (1), together with tremulenolide A (2) was isolated from the mangrove-derived fungus Flavodon flavus PSU-MA201.The difuranylmethane derivative based on 1 is rare in natural products. Their structures were established by spectroscopic evidence.

Tetrahydroanthraquinone and xanthone derivatives from the marine-derived fungus Trichoderma aureoviride PSU-F95.

Trichodermaquinone (1) and trichodermaxanthone (2) were isolated from the marine-derived fungus Trichoderma aureoviride PSU-F95 together with eleven known compounds. The structures were interpreted by spectroscopic methods. Known coniothranthraquinone 1 and emodin displayed strong antibacterial activity against methicillin-resistant Staphylococcus aureus with the MIC values of 8 and 4 μg/mL, respectively.

Sesquiterpene and xanthone derivatives from the sea fan-derived fungus Aspergillus sydowii PSU-F154.

Three new sesquiterpenes, named aspergillusenes A and B and (+)-(7S)-7-O-methylsydonic acid, and two new hydrogenated xanthone derivatives, named aspergillusones A and B, were isolated from the sea fan-derived fungus Aspergillus sydowii PSU-F154 together with 10 known compounds. Their structures were identified on the basis of spectroscopic data. The isolated compounds were evaluated for their antioxidant activity.

Modiolide and pyrone derivatives from the sea fan-derived fungus Curvularia sp. PSU-F22.

Investigation of secondary metabolites from the sea fan-derived fungus Curvularia sp. PSU-F22 resulted in isolation of three new metabolites, curvulapyrone (1), curvulalide (2) and curvulalic acid (3) together with six known compounds, modiolides A (4) and B (5), pyrenolide A (6), stagonolide E (7), mycoepoxydiene (8), and deacetylmycoepoxydiene (9). Their antimicrobial activity against Staphylococcus aureus ATCC 25923, methicillin-resistant S.

Anthraquinone, cyclopentanone, and naphthoquinone derivatives from the sea fan-derived fungi Fusarium spp. PSU-F14 and PSU-F135.

Five new metabolites, fusaranthraquinone (1), fusarnaphthoquinones A-C (2-4), and fusarone (5), were isolated from the sea fan-derived fungi Fusarium spp. PSU-F14 and PSU-F135 along with 18 known compounds. The structures were elucidated on the basis of spectroscopic evidence.

Lactone derivatives from the marine-derived fungus Penicillium sp. PSU-F44.

Two new fungal metabolites, penicipyrone (1), and penicilactone (2), were isolated from the marine-derived fungus Penicillium sp. PSU-F44 along with three known macrolides, (+)-brefeldin A (3), (+)-brefeldin C (4), and 7-oxobrefeldin A (5). Their antimicrobial activities against methicillin-resistant Staphylococcus aureus SK1 and Microsporum gypseum SH-MU-4 were examined.