Publications by authors named "Sita Bierma Zeinstra"

Objective: To study the association between various radiographic definitions of acetabular dysplasia (AD) and incident radiographic hip osteoarthritis (RHOA), and to analyze in subgroups.

Methods: Hips free of RHOA at baseline and with follow-up within 4-8 years were drawn from the World COACH consortium. The Wiberg center edge angle (WCEA), acetabular depth width ratio (ADR), and the modified acetabular index (mAI) were calculated.

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Objective: To determine the association between patient-reported spinal morning stiffness and lumbar disc degeneration (LDD) and systemic inflammation, as measured by C-reactive protein (CRP), in older patients with non-specific back pain. The ultimate objective is to help shape a future definition of spinal osteoarthritis (OA).

Design: Baseline data from the Dutch "Back Complaints in the Older Adults" (BACE) study was used.

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Background: We currently lack clear definitions for structural and symptomatic spinal osteoarthritis (OA). To define spinal OA and create diagnostic criteria for this condition, it is necessary to determine the relationship between clinical signs and symptoms of back pain and radiographic features of OA. Notably, recent studies suggest a defining sign of spinal OA could be a limited or painful spinal range of motion (ROM).

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Objective: To determine the efficacy of genicular artery embolisation (GAE) compared with sham GAE for pain reduction in patients with symptomatic mild-to-moderate knee osteoarthritis (KOA).

Design: Double-blind randomised sham-controlled clinical trial conducted from June 2019 to December 2021. The follow-up period was 4 months.

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Article Synopsis
  • Knee pain is a common issue among 13-year-olds, with a prevalence of 8% and a high rate of chronic cases (92.3% lasting over 3 months).
  • Most knee pain occurs on the front of the knee, with 37.5% of affected children experiencing pain daily.
  • Children with knee pain tend to have higher body mass indexes, and structural abnormalities like Osgood-Schlatter disease and bipartite patella were more frequently observed in them via MRI.
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Objectives: To determine the association between baseline cam morphology and self-reported hip pain assessed at annual visits over a 10-year follow-up period stratified by biological sex. The secondary aim was to study the association between the magnitude of cam morphology and the severity of pain in symptomatic hips.

Methods: The nationwide prospective Cohort Hip and Cohort Knee (CHECK) study includes 1,002 participants aged 45-65 years.

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Article Synopsis
  • The study aimed to create and validate diagnostic prediction models for diagnosing structural spinal osteoarthritis (OA) in older patients experiencing back pain, addressing the challenge of relying solely on imaging.
  • Three models were developed using data from a cohort of 669 older adults, incorporating factors like age, gender, and back pain characteristics, with the combined model showing the best performance and clinical utility.
  • Results suggest that while the models demonstrate potential for aiding clinicians in identifying structural spinal OA, they require further refinement and external validation before being used in clinical practice.
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  • The study aimed to explore different subtypes of cam morphology on hip radiographs and their link to developing radiographic hip osteoarthritis (RHOA) over ten years.
  • The CHECK study included over 1,000 participants aged 45-65, analyzing the relationship between specific cam morphology shapes and the onset of RHOA, with results indicating varying risk factors based on sex.
  • Four distinctive cam morphology subtypes were identified, with only certain subtypes acting as risk factors for RHOA, suggesting that cam morphology should be analyzed beyond just the alpha angle measurement.
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Objective: The objective is to determine the association and absolute risk of femoroacetabular impingement syndrome (FAIS) for the development of radiographic hip osteoarthritis (RHOA).

Methods: This is a nationwide, multicentre prospective cohort study (Cohort Hip and Cohort Knee) with 1002 individuals aged between 45 and 65 years. Hips without definitive RHOA (Kellgren-Lawrence (KL) grade≤1) at baseline and with anteroposterior pelvic radiographs at baseline and 10-year follow-up available (n=1386 hips) were included.

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Objective: No established definition for early-stage knee osteoarthritis (KOA) is available, nor classification criteria. Identifying the characteristics of individuals presenting with early-stage KOA symptoms can enhance diagnosis to prevent progression. This study aimed to describe clinical and structural features of individuals presenting with knee complaints within two years after their first consultation, while exploring differences in the duration of knee complaints.

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Objective: To provide a set of diagnostic criteria for early-stage hip osteoarthritis (OA) in primary care, using signs and symptoms monitored over 2 years in individuals with hip pain and/or stiffness. Additionally, the study aimed to see whether these factors were additive to factors based on baseline signs and symptoms only.

Methods: Data of the 543 persons with 735 symptomatic hips were collected from the prospective Cohort Hip and Cohort Knee cohort study.

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Objectives: The objective of this study is to develop classification criteria for overall hand osteoarthritis (OA), interphalangeal OA and thumb base OA based on self-reported data and radiographic features.

Methods: The classification criteria sets were developed in three phases. In phase 1, we identified criteria that discriminated hand OA from controls.

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Article Synopsis
  • A study aimed to find out the incidence of hand and wrist disorders in primary care, as previous data was limited due to a lack of specific coding for these issues.
  • The research analyzed medical records from over 200,000 patients in Rotterdam, focusing on new diagnoses between 2015 and 2019, and found average incidences of 5.9 per 1,000 person-years for hand disorders and 0.3 for wrist disorders.
  • The findings indicated a significant gap between actual patient presentations and documented diagnoses, suggesting that improved coding could enhance data accuracy and incidence tracking for these conditions.
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Importance: It has been demonstrated that total physical activity is not associated with risk of osteoarthritis. However, the association of different types of physical activity with incident knee osteoarthritis remains unclear.

Objective: To determine whether weight-bearing recreational physical activities are associated with increased risk of incident knee osteoarthritis.

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Purpose: Hip osteoarthritis (OA) is a major cause of pain and disability worldwide. Lack of effective therapies may reflect poor knowledge on its aetiology and risk factors, and result in the management of end-stage hip OA with costly joint replacement. The Worldwide Collaboration on OsteoArthritis prediCtion for the Hip (World COACH) consortium was established to pool and harmonise individual participant data from prospective cohort studies.

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Physical and mental health problems in music students are usually identified using self-reported data. The use of an Electronic Health Record database can avoid biases to give an overview of the extent of health problems in this population. Therefore, the aim of this study is to gain insight into both physical and mental health related issues in classical music students using this type of data collection.

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Background: Evidence-based practice for history-taking and physical examination in the evaluation of wrist complaints is limited.

Purpose: To create a set of recommended diagnostic tests for the clinical assessment of patients with undifferentiated wrist complaints.

Study Design: An e-Delphi study, following the recommendations on conducting and reporting Delphi studies, was performed.

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Musculoskeletal (MSK) pain is a common reason for consultation in general practice and frequently reported in children and adolescents. This study examined the prevalence of MSK pain in 13-year-old children and assessed associations with physical and psychosocial factors. Data from the Generation R Study, a population-based birth cohort, was used.

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Context: Before examining the impact of training load on injury risk in runners, it is important to gain insight into the differences between methods that are used to measure change in training load.

Objective: To investigate differences between 4 methods when calculating change in training load: (1) weekly training load; (2) acute : chronic workload ratio (ACWR), coupled rolling average (RA); (3) ACWR, uncoupled RA; (4) ACWR, exponentially weighted moving average (EWMA).

Design: Descriptive epidemiology study.

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Background: Many international clinical guidelines recommend therapeutic exercise as a core treatment for knee and hip osteoarthritis. We aimed to identify individual patient-level moderators of the effect of therapeutic exercise for reducing pain and improving physical function in people with knee osteoarthritis, hip osteoarthritis, or both.

Methods: We did a systematic review and individual participant data (IPD) meta-analysis of randomised controlled trials comparing therapeutic exercise with non-exercise controls in people with knee osteoathritis, hip osteoarthritis, or both.

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Article Synopsis
  • The study compares the effects of muscle strengthening training (MST) and behavioral graded activity (BGA) on pain relief for patients with knee osteoarthritis (KOA), focusing on inflammation and central sensitization as potential mechanisms.
  • It involves a three-arm clinical trial with 90 patients randomly assigned to either MST, BGA, or usual care, with assessments conducted at various intervals over 52 weeks.
  • The research seeks to clarify how these exercise therapies might reduce pain, aiming to benefit both scientific understanding and practical applications in pain management and exercise immunology.
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Background: Ankle sprains are frequent injuries in general practice. However, no effective treatment is available yet.

Aim: To examine the effectiveness of an unsupervised e-health-supported neuromuscular training programme in combination with usual care compared with usual care alone in patients with acute lateral ankle sprains in general practice.

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Objective: The objective of this study was to assess the relationship between pincer morphology and radiographic hip osteoarthritis (RHOA) over 2, 5, 8, and 10 years' follow-up and to study the interaction between pincer morphology and pain.

Methods: Individuals from the prospective Cohort Hip and Cohort Knee study were drawn. Anteroposterior pelvic and false profile radiographs were obtained.

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Objectives: To investigate hip dysplasia as a risk factor for clinically relevant and incident radiographic hip osteoarthritis.

Methods: From a prospective cohort (CHECK) of 1002 middle-aged, new consulters for hip and/or knee pain, 468 hips (251 individuals) were selected based on hip pain, available lateral center edge angle (LCEA) and absence of definite radiographic hip OA (Kellgren and Lawrence grade (KL) <2) at baseline, as well as available follow-up measures. Clinically relevant hip OA was defined by an expert diagnosis based on clinical and radiographic data obtained between year 5-10 from baseline.

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