Treatment of anal fissures using a combination of minoxidil and lignocaine: a randomized, double-blind trial.

Aim: Anal fissures are associated with hypertonia of the internal anal sphincter and pain. We evaluated the efficacy of local application of a combination of minoxidil and lignocaine in healing anal fissures.

Methods: In this prospective, randomized, double-blind study, 90 patients with anal fissure were recruited.