Publications by authors named "Sissi Xiang"

Background: The Pipeline Embolization Device (PED; Medtronic) has been used off-label for the treatment of challenging posterior circulation aneurysms. Data on this modality are primarily limited to small retrospective single-center series.

Objective: To assess safety and efficacy of this treatment by establishing an international, multicenter collaboration.

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Article Synopsis
  • - The study compared two endovascular flow diverters, the Pipeline Embolization Device (PED) and Flow Redirection Intraluminal Device (FRED), focusing on their effectiveness in treating posterior circulation aneurysms.
  • - Using a matched cohort design, researchers collected data from 375 treated aneurysms and found no significant differences in aneurysm occlusion or complication rates between the two devices.
  • - However, FRED demonstrated a higher rate of favorable functional outcomes (100% vs. 87.9%) compared to PED, suggesting the need for further research into these functional differences.
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