[Cardiorenal prognosis in kidney dysfunction patients undergoing cardiac surgery].

Aim: To evaluate the impact of cardiac surgical procedures on cardiac and renal functions within 12 months after surgery in patients with a history of chronic kidney disease (CKD).

Subjects And Methods: A total of 875 patients (464 men and 411 women) aged 32 to 68 years (62.3±5.

[THE RISK OF ACUTE RENAL LESIONS AND ITS PROGNOSTIC SIGNIFICANCE IN PATIENTS WITH CHRONIC RENAL DISEASE UNDERGOING CARDIAC SURGICAL INTERVENTION].

Aim: to determine the frequency and risk factors of acute renal lesions (ARL) and their prognostic significance in patients with chronic renal disease (CRD) undergoing surgical intervention.

Materials And Methods: The study included 1122 patients (586 men and 536 women) aged 32-68 (mean 62.3 ± 5.

[Predictive Value of Renal Dysfunction for Early and Long-Term Outcomes of Coronary Artery Bypass Grafting].

Aim: to assess value of renal dysfunction for immediate and long-term prognosis after coronary artery bypass grafting (CABG).

Material And Methods: We examined 657 patients (419 men and 238 women) aged 54-68 (60.6 ± 5.

[Effect of a fixed-dose perindopril and amlodipine combination on intrarenal hemodynamic and kidney functional parameters in patients with essential hypertension].

Aim: To evaluate the effect of prestans on intrarenal hemodynamic and kidney functional parameters and to study their correlations during 24-week therapy in patients with grade I-II essential hypertension (EH).

Subjects And Methods: Eighty-two patients (44 men and 38 women) with EH were examined and allocated to 3 groups according to glomerular filtration rate (GFR): 1) 31 patients with a GFR of > 90 ml/min/1.73 m2; 2) 28 with a GFR of 60-89 ml/min/1.

[Organoprotective effects of the combination of perindopril and amlodipine depending on the renal functional state in patients with arterial hypertension].

Aim: To estimate effect of combined perindopril/amlodipine therapy on structural and functional characteristics of the heart and blood vessels, intrarenal hemodynamics in patients with essential arterial hypertension (AH) depending on the degree of renal dysfunction.

Material And Methods: 112 patients (63 men and 49 women) were included in the study; 35 of them (group 1) had the glomerular filtration rate (GFR) 90 ml/min/1.73 m2 or higher, 43 (group 2)--60-89 ml/min/1.

[The influence of vascular remodeling and endothelial vasomotor function on the efficacy of indapamide retard in patients with hypertensive disease].

The influence of vascular remodeling and endothelial vasomotor function on the efficacy of indapamide retard was studied in 92 patients (49 men and 43 women) with stage I-II hypertensive disease and grade I-II arterial hypertension by observation of dynamics of the results of 24 hour AP monitoring and heart rhythm variability (HRV), cardio- and vasoprotective efects. The patients were divided into comparable groups. Group 1 was comprised of 40 patients without structural changes of the humeral artery (HA), group 2 included 52 patients undergoing HA remodeling.

[Impact of subclinical primary hyperparathyroidism on cardiovascular manifestations of essential arterial hypertension].

At 95 patients with essential arterial hypertension features of structural and functional remodeling of left ventricular and humeral artery depending on a level parathyroid hormone in blood are studied. It is shown that while increasing of plasma parathyroid hormone level frequency and expressiveness of left ventricular and humeral artery remodeling increases whereas diastolic function and endothelium-dependent vasodilatation considerably decrease. Subclinical primary hyperparathyroidism in patients with essential arterial hypertension is detected in 22.

[Selection of rational combinations of indapamide with various of calcium antagonists in patients with arterial hypertension].

We studied 89 patients with II degree arterial hypertension (age 43-67 years). Before and in 24 weeks after therapy we carried out 24-hour monitoring of arterial pressure and Doppler echocardiography. Patients were divided into 2 groups.

[Comparative efficiency of indapamide combinations with various derivaties of calcium antagonists in patients with arterial hypertension].

The study included 59 patients aged 42-65 yr with grade II AH. They underwent 24 hour AP monitoring and Doppler echocardiography before and 16 weeks after onset of the study. The patients were randomly allocated to 2 groups.

[Efficacy of calcium antagonists depending on the functional state of parathyroid glands in patients with hypertensive disease].

Hypotensive and cardioprotective effects of amlodipine (normodipine) were evaluated in 65 patients (35 men and 30 women) with grade II essential arterial hypertension treated with regard for calcium-controlling parathyroid function. 24 hour Holter monitoring, Doppler-cardiography, and blood PTH measurement were performed before and 6 months after the onset of therapy. The patients were divided into 3 groups depending on PTH levels (0-25, 26-50, and over 51 pg/ml).