Publications by authors named "Sis Aghayants"
Background: The high invasion and heterogeneity of head and neck squamous cell carcinoma (HNSCC) commonly leads to poor clinical outcomes. Identification of reliable biomarkers for HNSCC is imperative.
Methods: The targeted gene with the highest mutation was screened out in cBioPortal database, and the interactive microRNAs (miRNAs) were identified by miRNA-mRNA co-expression analysis.
Impact of vertical facial type on alveolar bone thickness and tooth morphology: A retrospective CBCT-based clinical study.
J Stomatol Oral Maxillofac Surg
October 2024
Article Synopsis
- The study investigates the link between vertical facial patterns and the structure of alveolar bone and teeth, which is important for effective orthodontic treatment planning.
- Researchers analyzed 300 cone-beam computed tomography scans from orthodontic patients, focusing on alveolar bone thickness and the crown and root dimensions of maxillary anterior teeth across different facial types.
- Results showed that short facial types had thicker alveolar bone compared to normal and long facial types, emphasizing the need to consider facial type during orthodontic planning.
The emerging modulators of non-coding RNAs in diabetic wound healing.
Front Endocrinol (Lausanne)
October 2024
Diabetic wound healing is a complex physiological process often hindered by the underlying metabolic dysfunctions associated with diabetes. Despite existing treatments, there remains a critical need to explore innovative therapeutic strategies to improve patient outcomes. This article comprehensively examines the roles of non-coding RNAs (ncRNAs), specifically microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), in regulating key phases of the wound healing process: inflammation, angiogenesis, re-epithelialization, and tissue remodeling.
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