Degradation of antidepressant drug fluoxetine in aqueous media by ozone/H2O2 system: process optimization using central composite design.

The main objective of this work is the modelling and optimization of antidepressant drug fluoxetine degradation in aqueous solution by ozone/H2O2 process using central composite design. The operational parameters were ozone concentration, initial hydrogen peroxide concentration, reaction time and initial fluoxetine concentration. A good agreement between the predicted values of fluoxetine removal and experimental results were observed (R2=0.

A modelling study and optimization of catalytic reduction of NO over CeO2-MnOx (0.25)-Ba mixed oxide catalyst using design of experiments.

In this study, the effects of operation variables on catalytic performance of CeO2-MnOx (0.25)-Ba mixed oxide in catalytic reduction of NO with ammonia are investigated by using design of experiments. A response surface methodology (RSM) combined with the central composite design (CCD) is used to model and optimize the process variables, including concentration of 02 (vol.