SAH-Induced Electrophysiological Changes of Ventricular Myocytes and Role of N-acetylcysteine Protection.

Background:  Electrocardiogram (ECG) changes in patients with subarachnoid hemorrhage (SAH) are frequent. ST- and/or T-wave changes in ECG seem to predominate.

Study Aims:  To investigate the ion channel mechanisms of SAH-induced ventricular excitation-contraction coupling changes and the possible protective effect of N-acetylcysteine (NAC).

Can Hypo/Hypernatremic Conditions be a Factor for Na Ion Channel Kinetics: Model Study.

Aim: Dysnatremic cases are frequently faced in clinical practice. Its macroscopic effects and consequences are well known, but microscopic effects are not well defined. The aim of this study was to reveal the effects of dysnatremia at the cellular level.