Publications by authors named "Siriwan Sriwong"
Oral calcium and calcium plus vitamin D supplements are commonly prescribed to several groups of patients, e.g., osteoporosis, fracture, and calcium deficiency.
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- Acute ischemia-reperfusion (I/R) injury is a leading cause of acute renal failure, characterized by endothelial cell dysfunction and microvascular injury, and EPO has shown protective effects in prior models of I/R injury.
- This study aimed to explore whether EPO administration could protect against renal failure caused by I/R injury in rats by enhancing the mobilization of endothelial progenitor cells (EPCs) and promoting blood vessel formation (neovascularization).
- Results indicated that EPO treatment improved renal function, reduced tubular damage, and increased levels of markers for EPCs and angiogenesis compared to the I/R group without EPO.
Article Synopsis
- Contrast-induced nephropathy (CIN) is a major cause of acute kidney injury in hospitals, linked to oxidative stress caused by intravenous radiocontrast agents.
- A study was conducted on male rats to assess the effects of alpha-tocopherol (a form of Vitamin E) on reducing kidney damage from CIN, with various groups receiving different doses prior to CIN induction.
- Results showed that alpha-tocopherol significantly improved renal function, reduced oxidative stress markers, and prevented kidney damage, suggesting its potential as an antioxidant therapy for CIN.