Publications by authors named "Sirithilak Gamage"
Phenotypic and genotypic distribution of ESBL, AmpC β-lactamase and carbapenemase-producing Enterobacteriaceae in community-acquired and hospital-acquired urinary tract infections in Sri Lanka.
Pandithage Dona Vindya Madushika Perera Sirithilak Gamage Hembadura Sara Melros De Silva Sashika Kushlani Jayatilleke Nelun de Silva
J Glob Antimicrob Resist
September 2022
Article Synopsis
- The study investigates the prevalence of β-lactamase production in urinary pathogens from two hospitals in Sri Lanka, an area with high antimicrobial resistance (AMR) concerns.
- A significant portion of urinary tract infections (UTIs) were caused by Escherichia coli, with high rates of extended-spectrum β-lactamase (ESBL), AmpC β-lactamase, and carbapenemase detected, especially in hospital-acquired cases.
- The study highlights alarming findings, such as the coexistence of multiple resistance genes and the association of beta-lactamase-producing infections with specific risk factors like age, previous hospitalization, and chronic illnesses.
Background: Varicella during pregnancy can lead to serious maternal and fetal consequences. Although an effective vaccine is available it is not incorporated in to the routine vaccination programs in most of the Asian countries. Objectives of the study were to determine the susceptibility to varicella and factors associated with immunity, among a group of pregnant women attending to a tertiary care hospital in Sri Lanka.
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