Hydroxyapatite nanoparticles formed under a wet mechanochemical method.

Hydroxyapatite (HA) nanoparticles were synthesized using a wet mechanochemical method without a calcination process. Dicalcium phosphate dihydrate (CaHPO ·2H O) and calcium carbonate (CaCO ) were mixed and milled in a planary mill using ethanol or water as liquid media in the two different synthesized routes. Effects of rotation speed and milling time on the final products formed have been studied.