Langerhans' cell histiocytosis (LCH) in adolescence presented with central diabetes insipidus: a case report.

A 19-year-old Thai man presented with symptoms of central diabetes insipidus, exopthalmos and multiple ostolytic lesions of the cranial vault. Skin biopsy showed strongly positive CD 1a and S100. Electron microscopy showed rod shape and pentalaminar granules called "Birbeck" granules, a diagnosis compatible with Langerhans' cell histiocytosis (LCHs) or histiocytosis X.

Benign and malignant soft tissue mass: magnetic resonance imaging criteria for discrimination.

Objective: Determine MRI features to differentiate between benign and malignant lesions.

Material And Method: The Magnetic resonance imaging (MRI) taken in the 5-year period (2003-2007) of 85 patients with benign and malignant soft tissue masses were analyzed. The criteria for discrimination were based on size, origin, signal homogeneity on T1- and T2-weighted, perilesional edema or invasion, hemorrhage, necrosis, and bone and neurovascular involvements.