The study focuses on evaluating the effectiveness of PET-CT scans for staging lymph nodes in patients with locally advanced cervical cancer (LACC) who underwent treatment with pelvic chemoradiotherapy.
Researchers analyzed data from 71 patients who had PET-CT scans followed by a surgical procedure called para-aortic lymphadenectomy, assessing the accuracy of the scans through various metrics like sensitivity and specificity.
The results showed that while the PET-CT had a high specificity (84%) and negative predictive value (93%), its overall sensitivity (55%) and positive predictive value (33%) were lower, suggesting the need for surgical staging in certain high-risk cases despite a negative PET-CT result.