Publications by authors named "Sirinapa Thangsiri"

Article Synopsis
  • Cyanobacteria, particularly the species Arthrospira, are rich in nutrients and natural pigments with numerous health benefits, prompting a study to optimize their extraction for maximum phenolic content and antioxidant activity.
  • Through specific methods, the research determined effective extraction conditions that enhanced the yield of beneficial compounds, with A. maxima outperforming A. platensis in terms of bioactive content and enzyme inhibition properties.
  • The study reveals that both species can inhibit key enzymes related to diseases like diabetes and Alzheimer's, with a notable synergy found between Arthrospira extracts and the Alzheimer's drug donepezil in inhibiting a critical enzyme linked to the disease.
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This study developed a food-grade fermentation process that efficiently isolated proteins and minerals from shrimp-processing waste (SPW). The in vitro antioxidant and enzyme inhibitory effects of SPW hydrolysates obtained from the fermentation process were investigated. SPW broths were prepared from the head (SPW-SH) and body carapace (SPW-SS) of Pacific white shrimp () and fermented using a 5-day successive co-culture fermentation approach with TISTR-1880 and TBRC-388.

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The physicochemical and functional properties, structures, and nutritional characterizations of Hodgsonia heteroclita oilseed cake powder (OCP) obtained from oil extraction with no pretreatment (NP), heat pretreatment (HP; drying at 55 °C until reaching 10% moisture content), and the combined heat and enzymatic pretreatment (HEP; 2.98% (w/w) enzyme loading, 48 °C of incubation temperature and 76 min of incubation time) were investigated. HP and HEP caused a decrease in lightness but an increase in the yellow-brown color of OCP.

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Plant phenolics have been known for various biological activities. This study aims to extract and examine the presence of phenolics in Bao mango (Mangifera indica L. var.

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A previous study reported that the ethanolic extract of the edible fern, (Retz.) Sw. (DE), obtained from a non-optimized extraction condition exhibited anti-Alzheimer's disease (AD) properties through the inhibition of a rate-limiting enzyme in amyloid peptide formation, β-secretase-1 (BACE-1).

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L., a parasitic root in the Orobanchaceae family, is used as a food colorant in traditional Thai desserts. However, scant information is available on its food applications as well as medicinal properties, while overharvesting by the local people has severely depleted wild plant populations.

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Most biowaste produced by domestic food preparation and food processing has no value, is difficult to manage, and is detrimental to the environment. Oil extraction from seeds produces large amounts of oilseed cake powder (OCP) as biowaste. The extraction of residual phytochemicals using simple and eco-friendly methods can increase the economic utility of OCP.

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Article Synopsis
  • * This research focused on the phenolic profiles and health benefits of 29 herbal ingredients in two Thai remedies, finding some with potential to combat chronic diseases.
  • * Notable extracts showed promise: Biancaea sappan scored highest for antioxidant potential, Bouea macrophylla inhibited diabetes-related enzymes, Dischidia major targeted hypertension, and Dracaena cochinchinensis could aid in Alzheimer's treatment.
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Rice () is a staple food crop for over half of the world's population. However, drought as a result of climate change has led to increased soil salinity, thereby reducing agricultural potential, especially rice nutritional compositions and biochemical properties. Nevertheless, soil management by using suitable fertilizers might be able to improve rice quality even though these rice samples were grown in soil with a high degree of salinity.

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The cold brew coffee (CBC) trend is increasing globally; nevertheless, there is limited literature on this popular beverage. Many studies have focused on the health benefits of green coffee beans and coffee brewed by conventional hot water methods. Thus, whether cold brew conveys similar benefits is still unclear.

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In the present study, response surface methodology (RSM) and Box-Behnken design (BBD) were employed to optimize the conditions for the extraction of albedo from agricultural waste, to obtain notable phytochemicals. Ethanol concentration, extraction temperature, and extraction time were included as key factors contributing to the extraction. The results showed that the optimum extraction condition for albedo was 50% (/) aqueous ethanol at 30 °C for 4 h, which provided total phenolic contents and total flavonoid contents at 15.

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Article Synopsis
  • - The
  • sacred lotus
  • is widely used in Asia for food and traditional medicine due to its high levels of beneficial compounds like phenolics and alkaloids.
  • - A study examined the
  • seasonal variations
  • in total phenolic contents and their related health benefits across different parts of the lotus plant, finding that the stamen consistently showed
  • higher antioxidant activities and enzyme inhibitions
  • relevant to chronic diseases.
  • - The
  • best time
  • to harvest lotus stamen for its health benefits is at the
  • beginning of the rainy season
  • , as it has significantly higher phenolic content and biochemical activities compared to other seasons, providing valuable information for lotus cultivation and potential future product development.
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Kurz is an evergreen tree in the family, mostly found in the forests of some Southeast Asia countries, especially Thailand. The lack of biological information regarding this tree has led to inappropriate agricultural management, conservation and utilization. Thus, this study aims to examine the nutritional composition, organic acid and phenolic profiles and in vitro health properties through several key enzyme inhibitions against some civilization diseases including Alzheimer's disease (β-secretase (BACE-1), butyrylcholinesterase (BChE) and acetylcholinesterase (AChE)), obesity (lipase), hypertension (angiotensin-converting enzyme (ACE)) and diabetes (dipeptidyl peptidase-IV (DPP-IV), α-amylase and α-glucosidase) on the aril (flesh) part of Kurz fruit.

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Article Synopsis
  • The study focuses on extracting oil from a neglected crop called subsp. W.J.de Wlide & Duyfjes (or Making in Thai), which has nuts high in fat content.
  • Using response surface methodology (RSM), researchers determined that a mixture of Flavourzyme and Viscozyme led to a maximum oil yield of 46.44% under optimal conditions (2.98% enzyme, 48°C, 76 min).
  • The extracted oil demonstrated favorable chemical properties and higher levels of beneficial compounds like δ-tocopherol and omega-6 fatty acids, marking this as the first report on enzyme-assisted extraction from this plant for vegetable oil production.
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Legumes and pulses are important food components with various phytochemicals and health benefits. However, the health-related bioactivities of some underutilized species remain uninvestigated. To breed a new bean lineage with particular health-related properties, this study investigated phenolics (specifically, isoflavones) and the in vitro inhibitory activities of the enzyme relevant to some non-communicable diseases in underutilized cultivars of (lima beans), compared to the commonly consumed (red kidney bean) and beans in the and genera.

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Undernutrition and mineral deficiencies negatively impact both the health and academic performance of school children, while diets high in phytic acid and some phenolics inhibit the absorption of minerals such as iron and zinc. This study developed instant porridge powders rich in iron and zinc using pregelatinized chickpea flour (PCPF) and pregelatinized foxtail millet flour (PFMF) and assessed the potential of utilizing roselle calyx powder (RCP) as a source of organic acids to enhance its iron and zinc bioaccessibility. Physical properties, nutrients, mineral inhibitors and in vitro iron and zinc bioaccessibility of different proportions of PCPF, PFMF and RCP in instant porridge powders were evaluated.

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Legumes and pulses are nutrient-dense foods providing a good source of protein, complex carbohydrates, fiber, vitamins, minerals, and bioactive compounds. To breed a new lineage of beans with specific nutritional and health beneficial purposes, more information on original lineage beans must be obtained. However, data concerning the nutritive compositions, total phenolic contents (TPCs), and health benefits regarding the antioxidant potentials of some original lineage beans in Thailand remain scarce, causing difficulty in decisional selection to breed a new lineage.

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Thailand has vast areas of tropical forests with many indigenous plants, but limited information is available on their phytochemical profile and in vitro inhibitions of enzymatic and nonenzymatic reactions. This study investigated phenolic profiles using liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS), antioxidant activities, and in vitro inhibitory activities of 10 indigenous plants on key enzymes related to obesity (lipase), diabetes (α-amylase and α-glucosidase), and Alzheimer's disease (cholinesterases and β-secretase). The nonenzymatic anti-glycation reaction was also investigated.

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Craib. is an indigenous plant found in Thailand, Cambodia and Vietnam that has become threatened owing to lack of knowledge about its agricultural management. This plant is now rare in the wild and was registered in the Plant Genetic Conservation Project under the initiation of Her Royal Highness Princess Maha Chakri Sirindhorn (RSPG) to promote sustainable conservation and optimally beneficial utilization.

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Article Synopsis
  • The sacred lotus has been used in traditional remedies and contains compounds that may help prevent Alzheimer's disease (AD) through inhibition of key enzymes.
  • Different methods (especially aqueous extraction) were tested to analyze bioactive compounds in parts of the sacred lotus, like its stamen, which showed high levels of antioxidants and enzyme-inhibitory properties.
  • Research suggests that combining the stamen, old leaf, and petal can enhance the health benefits of sacred lotus, particularly in fighting AD, but more studies are needed to fully understand these interactions.
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Article Synopsis
  • - Alzheimer's disease (AD) is a progressive condition affecting the brain, and natural products like mulberry, which have antioxidant properties and can inhibit specific enzymes linked to AD, are being researched for potential benefits against the disease.
  • - Mulberry trees from different locations may have varying amounts of healthy phytochemicals, complicating comparisons between different types of mulberries.
  • - A study of twenty-seven mulberry species in Thailand revealed that one particular cultivar (SKSM 810191) stood out for its high content of beneficial phytochemicals, strong antioxidant activities, and effective inhibition of key enzymes related to AD, making it a promising candidate for further research.
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