Publications by authors named "Sirin Ceylan"

Article Synopsis
  • Leishmaniasis, caused by the Leishmania protozoa, affects around 12 million people across 98 countries, particularly in tropical and subtropical regions, with 1.2 million new cases reported yearly and rising drug resistance complicating treatment.
  • Recent research has focused on plant-derived substances as potential anti-leishmanial agents, with this study investigating the effects of extracts from Prangos ferulacea and Ferula orientalis against Leishmania tropica.
  • The results indicate that certain extracts from these plants exhibit significant cytotoxic activity against L.tropica, with P. ferulaceae showing the lowest IC50 values and specific extracts also impacting non-target mammalian cells.
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In this study, we aimed to investigate the incidence of Dientamoeba fragilis with different diagnostic methods in patients with gastrointestinal symptoms and determine the sensitivity and specificity of existing diagnostic methods. Fecal samples collected from 101 patients with gastrointestinal complaints (especially upper abdominal pain, abdominal and pelvic pain, nausea and vomiting, gastroenteritis and colitis, unexplained fever and diarrhea) and 20 control cases from various clinics were included in the study. Samples were first examined with native-Lugol (N-L) method and cultured in Robinson medium.

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Malaria is caused by the protozoan parasite Plasmodium, the leading cause of death amongst the parasitic diseases. The disease is transmitted to human by the bites of female Anopheles mosquitoes. According to the World Health Organization (WHO) data, there were an estimated 214 million malaria cases and estimated 438.

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Objective: Leishmaniasis is caused by an obligate intracellular protozoa belonging to Leishmania genus and listed among major tropical diseases by WHO. Because of the high costs, toxicity, and adverse effects of routinely used compounds in the treatment, alternative treatment and vaccine studies are underway. An effective vaccine has not been developed to date.

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Objective: To compare maternal and neonatal outcomes of the vaginal delivery versus cesarean delivery for the breech presentation.

Methods: We reviewed the maternal and neonatal charts of all singleton breech deliveries of <1,000, 1,000-1,500, 1,501-2,500, 2,501-4,000, and >4,000 g delivered between 2000 and 2006 at our institution. The study population consisted of 1,537 women with a fetus in a breech presentation.

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Case Report: A 28-year-old patient gravida 3, para 2 was admitted at 16 weeks' gestation with the diagnosis of complete hydatidiform mole with coexistent live fetus (CHMCF) in dichorionic twin gestation. The betaHCG level was 530,000 mIU/ml. The pregnancy was terminated by hysterotomy.

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