Morphometric and volumetric analysis of the proximity between the incisive canal and maxillary central incisors during anterior retraction: a retrospective cone-beam computed tomography study.

Objectives: To elucidate the relationships and factors affecting the proximity between the incisive canal (IC) and maxillary central incisors and to predict the probable outcomes after anterior tooth retraction using cone beam computed tomography (CBCT).

Materials And Methods: Retrospective CBCT data taken before and after maxillary anterior retraction in 36 patients were used in this study. The incisive canal length (ICL), maxillary central incisor length (TL), angles between the palatal plane and axes of the maxillary alveolar border (θ1), IC (θ2), and maxillary central incisor (θ3), retraction distance (TDE), distance from the maxillary central incisors to the IC (D), cross-sectional area of the IC (CSA), and volume of the IC were evaluated.

Effects of local vs systemic administration of CXCR4 inhibitor AMD3100 on orthodontic tooth movement in rats.

Introduction: Chemokines play pivotal roles in orthodontic tooth movement (OTM) through osteoclast-mediated bone resorption, but the underlying mechanism remains unclear. We aimed to elucidate the effects of serial local vs systemic administration of the chemokine receptor CXCR4 antagonist AMD3100 on OTM.

Methods: The maxillary first molar (M1) of rats was moved mesially using a 10 g of force nickel-titanium coil spring.