Publications by authors named "Siriluk Maskaew"
Prophenoloxidase (proPO) activating enzymes, known as PPAEs, are pivotal in activating the proPO system within invertebrate immunity. A cDNA encoding a PPAE derived from the hemocytes of banana shrimp, Fenneropenaeus merguiensis have cloned and analyzed, referred to as FmPPAE1. The open reading frame of FmPPAE1 encompasses 1392 base pairs, encoding a 464-amino acid peptide featuring a presumed 19-amino acid signal peptide.
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- Serine proteases play key roles in various biological systems, with a specific one from Vibrio parahaemolyticus identified as a virulence factor.
- A mutated version of the serine protease gene from V. parahaemolyticus was used to create a DNA vaccine, which effectively expressed in different tissues of the white shrimp, Litopenaeus vannamei.
- Vaccinated shrimp showed significantly lower mortality rates and enhanced immune responses compared to controls, indicating the potential of this DNA vaccine as a preventative measure against AHPND in shrimp.
Numerous lectins act as pattern recognition receptors (PRRs) in the innate immune system of invertebrates. Here, a galectin (FmGal) was isolated from hemocytes of Fenneropenaeus merguiensis. FmGal contained one open reading frame encoding a peptide of 338 amino acids.
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