Kaposi's sarcoma, epidemiology and clinical characteristics in a tertiary hospital, a cross-sectional study.

Introduction: Kaposi's Sarcoma (KS) is a rare soft tissue tumor linked to human herpesvirus 8 (HHV-8), a recognized oncogenic virus. Five distinct clinical presentations have been identified, with the epidemic type being the most prevalent and notably associated with Human Immunodeficiency Virus (HIV). A delayed diagnosis significantly compromises patient prognosis and survival rates.

[Anti-MDA5 dermatomyositis. Literature review].

Dermatomyositis positive anti-melanoma differentiation-associated gene 5 (anti-MDA5 DM) is a rare disease that represents less than 2%. The prevalence of anti-MDA5 DM ranges from 7 to 60%, with higher prevalence in Asian (11-60%) and women. The clinical picture may be variable and is accompanied by the typical features of dermatomyositis, such as periorbital heliotrope (blue-purple) rash with edema, erythematous rash on the face, or the anterior chest (in a V-sign), and back and shoulders (in a shawl sign), violaceous papules or plaques located on the dorsal part of the metacarpophalangeal or interphalangeal joints, which are pathognomonic by definition; yet, one of the most striking signs is the painful ulceration skin that is found in 82% of cases, which is deep and in punching holes or showing hyperkeratotic crusts.