Publications by authors named "Sire N'Diaye"
NPJ Vaccines
November 2024
Article Synopsis
- - Neuraminidase (NA) is a key glycoprotein in the influenza virus that aids in replication, yet existing vaccines mainly target hemagglutinin (HA) instead of NA despite evidence linking NA antibodies to disease resistance.
- - Research showed that recombinant NA (rNA) is effective in eliciting immune responses in naïve mice and ferrets, even among those with existing immunity.
- - When rNA was added to a traditional HA-based vaccine, it significantly enhanced NA-specific immune responses in ferrets without compromising HA-specific immunity, suggesting a potential improvement in vaccine effectiveness.
