Publications by authors named "Sira Domenech-Puigcerver"
Article Synopsis
- INSTIs are crucial in current HIV treatment but their effects on brain health are not well understood.
- A study compared cognitive and brain function outcomes in men with HIV starting INSTI therapy within 3 months versus after 6 months of infection, alongside a control group.
- Findings showed no significant cognitive differences between the two HIV groups after 48 weeks, but those diagnosed earlier had poorer functional status initially, which improved over time; however, later initiators had more decline in a specific brain area linked to decision-making.
We report a case of acute-onset multifocal vertebral osteitis with a marked impact on the patient's general health. The radiological, scintigraphic and magnetic resonance findings made it necessary to carry out a differential diagnosis to distinguish it from an infiltrative neoplastic process and determine whether it had an infectious or an inflammatory etiology. The presence of noninfectious multifocal osteitis and sternoclavicular arthritis and the subsequent development of plantar pustulosis pointed to SAPHO syndrome.
View Article and Find Full Text PDFIntroduction: Neuromyelitis optica (NMO), or Devic's disease, is an autoimmune, inflammatory and demyelinating disease of the central nervous system which mainly and characteristically involves the optic nerve and the spinal cord. Anti-aquaporin-4 (AQ-4) antibodies are a specific biomarker of the entity and, since their discovery, both the number of symptoms and the radiological data about the disease have progressively increased, and the concept of clinical spectrum of NMO has been defined.
Case Report: A 66-year-old female diagnosed with NMO after suffering attacks of optic neuritis and recurrent myelitis, and showing positive for AQ-4 antibodies.