flagellin exacerbates colorectal cancer through activating LRRC19/TRAF6/TAK1 pathway.

The initiation and progression of colorectal cancer (CRC) are intimately associated with genetic, environmental and biological factors. (DSV), a sulfate-reducing bacterium, has been found excessive growth in CRC patients, suggesting a potential role in carcinogenesis. However, the precise mechanisms underlying this association remain incompletely understood.

Formulating Self-Repairing Solid Electrolyte Interface via Dynamic Electric Double Layer for Practical Zinc Ion Batteries.

Zinc ion batteries (ZIBs) encounter interface issues stemming from the water-rich electrical double layer (EDL) and unstable solid-electrolyte interphase (SEI). Herein, we propose the dynamic EDL and self-repairing hybrid SEI for practical ZIBs via incorporating the horizontally-oriented dual-site additive. The rearrangement of distribution and molecular configuration of additive constructs the robust dynamic EDL under different interface charges.

Isolation and characterization of GXUN74707 with efficient flocculation performance and application in wastewater treatment.

The identification of microorganisms with excellent flocculants-producing capability and optimization of the fermentation process are necessary for the wide-scale application of bioflocculants. Therefore, we isolated and identified a highly efficient flocculation performance strain of GXUN74707 from the sludge. The optimal fermentation and flocculation conditions of strain GXUN74707 was in fermentation medium with glucose and urea as the carbon and nitrogen sources, respectively, at pH 7.

Empowerment of the older adults in the context of Chinese culture: an evolutionary concept analysis.

Background: With the increasing focus on addressing the challenges of aging, researchers have begun to recognize the potential impact of empowering older individuals in addressing retirement issues. However, within different cultural contexts, there still needs to be a more precise analysis regarding the definition of empowering older individuals.

Objective: To define and analyze the concept of empowering older individuals within the cultural context of China.

Astragalin: a food-origin flavonoid with therapeutic effect for multiple diseases.

Naturally occurring flavonoids have long been utilized as essential templates for the development of novel drugs and as critical ingredients for functional foods. Astragalin (AG) is a natural flavonoid that can be isolated from a variety of familiar edible plants, such as the seeds of green tea, Morus alba L., and Cuscuta chinensis.

Corrigendum: Targeting matrix metalloproteases in diabetic wound healing.

[This corrects the article DOI: 10.3389/fimmu.2023.

Could Cyclosiversioside F Serve as a Dietary Supplement to Prevent Obesity and Relevant Disorders?

Obesity is the basis of numerous metabolic diseases and has become a major public health issue due to its rapidly increasing prevalence. Nevertheless, current obesity therapeutic strategies are not sufficiently effective, so there is an urgent need to develop novel anti-obesity agents. Naturally occurring saponins with outstanding bio-activities have been considered promising drug leads and templates for human diseases.

Procyanidin B2: A promising multi-functional food-derived pigment for human diseases.

Natural edible pigments play a paramount part in the food industry. Procyanidin B2 (PB2), one of the most representative naturally occurring edible pigments, is usually isolated from the seeds, fruits, and leaves of lots of common plants, such as grapes, Hawthorn, black soybean, as well as blueberry, and functions as a food additive in daily life. Notably, PB2 has numerous bioactivities and possesses the potential to treat/prevent a wide range of human diseases, such as diabetes mellitus, diabetic complications, atherosclerosis, and non-alcoholic fatty liver disease, and the underlying mechanisms were partially elucidated, including mediating signaling pathways like NF-κB, MAPK, PI3K/Akt, apoptotic axis, and Nrf-2/HO-1.

Targeting matrix metalloproteases in diabetic wound healing.

Chronic inflammation participates in the progression of multiple chronic diseases, including obesity, diabetes mellitus (DM), and DM related complications. Diabetic ulcer, characterized by chronic wounds that are recalcitrant to healing, is a serious complication of DM tremendously affecting the quality of life of patients and imposing a costly medical burden on society. Matrix metalloproteases (MMPs) are a family of zinc endopeptidases with the capacity of degrading all the components of the extracellular matrix, which play a pivotal part in healing process under various conditions including DM.

Bacillus pinisoli sp. nov., Isolated from Soil of a Decayed Pine Tree.

A Gram-stain-positive, rod-shaped, facultatively anaerobic, motile and spore-forming bacterium with multiple flagella designated GXH0341 was isolated from the soil associated with decayed pine tree samples collected from Weizhou Island, Beihai, Guangxi, China. Growth occurred at 4-37 °C (optimum 30 °C), at pH 5.0-11.

Comparative evaluation of short or standard implants with different prosthetic designs in the posterior mandibular region: a three-dimensional finite element analysis study.

The purpose of this study is to evaluate the stress distribution of splinted or nonsplinted restorations supported by 2 short or 2 standard dental implants in the mandibular molar region using three-dimensional finite element analysis. Two standard implants (4.8 × 10mm) were placed in the mandibular molar area.

Mowing Did Not Alleviate the Negative Effect of Nitrogen Addition on the Arbuscular Mycorrhizal Fungal Community in a Temperate Meadow Grassland.

As nitrogen deposition intensifies under global climate change, understanding the responses of arbuscular mycorrhizal (AM) fungi to nitrogen deposition and the associated mechanisms are critical for terrestrial ecosystems. In this study, the effects of nitrogen addition and mowing on AM fungal communities in soil and mixed roots were investigated in an Inner Mongolia grassland. The results showed that nitrogen addition reduced the α-diversity of AM fungi in soil rather than that of root.

Vegetation Greenness Dynamics in the Western Greater Khingan Range of Northeast China Based on Dendrochronology.

Understanding the vegetation greenness dynamics in the forest-steppe transition zone is essential for ecosystem management, and in order to study ecological changes in the region. This study provides a valuable record of the vegetation greenness dynamics in the western Greater Khingan Range over the past 193 years (1826-2018) based on tree-ring data represented by the normalized difference vegetation index (NDVI). The reconstructed vegetation greenness dynamics record contains a total of 32 years of high vegetation greenness and 37 years of low vegetation greenness, together occupying 35.

Leaf Functional Traits of Two Species Affected by Nitrogen Addition Rate and Period Not Nitrogen Compound Type in a Meadow Grassland.

Plasticity of plant functional traits plays an important role in plant growth and survival under changing climate. However, knowledge about how leaf functional traits respond to the multi-level N addition rates, multiple N compound and duration of N application remains lacking. This study investigated the effects of 2-year and 7-year N addition on the leaf functional traits of and in a meadow grassland.

Studies on reproductive strategies of L. var. (Franch.) Rehder (Lamiaceae) based on morphological characteristics and SSR markers.

L. var. (Franch.

The Impact of Health Insurance Policy on the Health of the Senior Floating Population-Evidence from China.

The impact of health insurance on residents' health is one of the focal points of academic research. Due to the fact that China's medical insurance system is composed of a variety of programs and that the pooling districts are at the lower administrative level, enrollment in different medical insurance programs or at different places may have certain influences on the health of residents. This has mostly been neglected by previous studies.