[Preliminary Study of the Role of INPP4B in Promoting Colorectal Cancer Metastasis and the Mechanisms Involved].

Objective: To investigate the expression of inositol polyphosphate 4-phosphatase type Ⅱ B (INPP4B) in colorectal cancer (CRC) and the relevant clinical significance, to determine the relationship between INPP4B and matrix metallopeptidase 7 (MMP7) in CRC cells, and to make preliminary exploration of the effects of INPP4B on the proliferation and migration of CRC cells and mechanisms involved.

Methods: The TIMER2.0 and GEPIA2 databases were used to analyze the differences in expression between cancer and para-cancerous tissues and the effects of such differences on the prognosis of CRC.

Insight into low methoxyl pectin enhancing thermal stability and intestinal delivery efficiency of algal oil nanoemulsions.

Background: Algae oil has garnered widespread acclaim due as a result of its high purity of docosahexaenoic acid (DHA) and excellent safety profile. The present study aimed to develop stable nanoemulsions (NEs) systems containing DHA from algae oil through thermal sterilization by combining modified whey protein concentrate (WPC) with low methoxyl pectin (LMP), as well as to investigate the impact of LMP concentration on the thermal stability and the gastrointestinal delivery efficiency of DHA NEs.

Results: The addition of LMP enhanced the stability of the emulsion after sterilization, at the same time as improving the protective and sustained release effects of DHA in the gastrointestinal tract.

[A systematic evaluation on the quality of Meta-analysis in articles published in National Medical Journal of China from 1998 to 2014].

Objective: To assess qualities on methodologies and reporting on Meta-analysis used in papers being published in National Medical Journal of China.

Methods: Computerized literature searching was performed in Wangfang Medical Online to collect articles that Meta-analysis was used in the National Medical Journal of China since January 1998 until October 2014. Manual retrieval was also conducted.

[A systematic evaluation on the quality of Meta-analysis in articles published in the Chinese Journal of Gastrointestinal Surgery from 1998 to 2014].

Objective: To assess the methodological quality and reporting quality on Meta-analysis being published in the Chinese Journal of Gastrointestinal Surgery.

Methods: Computerized literature searching was carried out in Wanfang Medical Online to collect articles that Meta-analysis was used in the Chinese Journal of Gastrointestinal Surgery since it was founded till July, 2014. Manual retrieval was also conducted.