A comprehensive, open-source data model for wastewater-based epidemiology.

The recent SARS-COV-2 pandemic has sparked the adoption of wastewater-based epidemiology (WBE) as a low-cost way to monitor the health of populations. In parallel, the pandemic has encouraged researchers to openly share their data to serve the public better and accelerate science. However, environmental surveillance data are highly dependent on context and are difficult to interpret meaningfully across sites.

Trends on Human Norovirus Virus-like Particles (HuNoV-VLPs) and Strategies for the Construction of Infectious Viral Clones toward In Vitro Replication.

Most acute gastroenteritis (AGE) outbreaks and sporadic cases in developing countries are attributable to infection by human norovirus (HuNoV), the enteric virus mainly transmitted via fecal-contaminated water. However, it has been challenging to study HuNoV due to the lack of suitable systems to cultivate and replicate the virus, hindering the development of treatments and vaccines. Researchers have been using virus-like particles (VLPs) and infectious viral clones to overcome this challenge as alternatives to fresh virus isolates in various in vitro and ex vivo models.

Giant phagocytes (Gφ) and neutrophil-macrophage hybrids in human carotid atherosclerotic plaques - An activated phenotype.

Introduction: A small subpopulation of CD66b+ neutrophils with extended lifespan and immensely large size was identified . They internalized dead neutrophil remnants and cellular debris, transforming them into giant phagocytes (Gφ) resembling macrophage-foam cells with a massive lipid content and CD68+ scavenger receptor expression. Thus, we sought to investigate if similar CD66b+ neutrophils with altered morphology and functions exist in inflammatory/atherosclerotic conditions , by using human carotid atherosclerotic plaques.

URSID γ-HERPESVIRUS TYPE 1-RELATED VIRUS IN CAPTIVE BORNEAN SUN BEARS () IN SABAH, MALAYSIA.

The Bornean sun bear () is the smallest subspecies of sun bear. Their numbers are declining, and more research is needed to better understand their health and biology. Forty-four bears housed at the Bornean Sun Bear Conservation Centre (BSBCC) in Sabah, Malaysia, were screened for known and novel viruses in November 2018.

Markers of Carotid Plaque Destabilization in Patients With Sleep-Disordered Breathing.

Sleep-disordered breathing (SDB) is a nightly respiratory condition characterized by intermittent hypoxia, leading to oxidative stress, inflammation, and atherosclerosis. However, most cellular markers of human carotid plaques in SDB have not yet been assessed. We aimed at characterizing the cellular, inflammatory, and nitro-oxidative stress markers in carotid plaques obtained from 25 patients undergoing endarterectomy and screened for SDB.

ACCRETION PROCESSES IN COSMIC SOURCES: The Atmospheres of Accreting White Dwarfs.

A comparison is presented between the physical processes operative in single white dwarfs and the physical processes operative in white dwarfs with donor star companions. The physical properties and accretion physics of the hot accreting components in close interacting binaries is presented. The N/C abundance anomaly seen is ∼10% of cataclysmic variables and the presence of absorption lines due to heavy elements in suprasolar abundance are discussed.

Modifying the Standard Disk Model for the Ultraviolet Spectral Analysis of Disk-dominated Cataclysmic Variables. I. The Novalikes MV Lyrae, BZ Camelopardalis, and V592 Cassiopeiae.

The standard disk is often inadequate to model disk-dominated cataclysmic variables (CVs) and generates a spectrum that is bluer than the observed UV spectra. X-ray observations of these systems reveal an optically thin boundary layer (BL) expected to appear as an inner hole in the disk. Consequently, we truncate the inner disk.

FUSE Spectroscopy of the Accreting Hot Components in Symbiotic Variables.

We have conducted a spectroscopic analysis of the far ultraviolet archival spectra of four symbiotic variables, EG And, AE Ara, CQ Dra and RW Hya. RW Hya and EG And have never had a recorded outburst while CQ Dra and AE Ara have outburst histories. We analyze these systems while they are in quiescence in order to help reveal the physical properties of their hot components via comparisons of the observations with optically thick accretion disk models and NLTE model white dwarf photospheres.

Far Ultraviolet Spectroscopy of Old Novae. II. RR Pic, V533 Her, and DI Lac.

The old novae V533 Her (Nova Her 1963), DI Lac (Nova Lac 1910), and RR Pic (Nova Pic 1891) are in (or near) their quiescent stage, following their nova explosions, and continue to accrete at a high rate in the aftermath of their explosions. They exhibit continua that are steeply rising into the FUV, as well as absorption lines and emission lines of uncertain origin. All three have () spectra that offer not only higher spectral resolution but also wavelength coverage extending down to the Lyman Limit.

Hubble COS Spectroscopy of the Dwarf Nova CW Mon: The White Dwarf in Quiescence?

We present a synthetic spectral analysis of the HST COS spectrum of the U Geminorum-type dwarf nova CW Mon, taken during quiescence as part of our COS survey of accreting white dwarfs in Cataclysmic Variables. We use synthetic photosphere and optically thick accretion disk spectra to model the COS spectrum as well as archival IUE spectra obtained decades ago when the system was in an even deeper quiescent state. Assuming a reddening of E(B-V)=0.

[Treatment of the acute diverticulitis: A systematic review].

Acute diverticulitis is a common disease with increasing incidence. In most of cases, diagnosis is made at an uncomplicated stage offering a curative attempt under medical treatment and use of antibiotics. There is a risk of diverticulitis recurrence.

Far Ultraviolet Spectroscopy of Old Novae I. V603 Aquila.

We present the results of a synthetic spectral analysis of the far ultraviolet archival IUE, HST and FUSE observations of the fast old nova V603 Aql, obtained some 90 years after its 1918 nova outburst. Our analysis utilizes the new Hubble FGS parallax distance for this nearly face-on old nova, a high white dwarf mass and a low reddening. Our analysis includes non-truncated optically thick accretion disks since V603 Aql is neither a polar nor an intermediate polar.

Gastric Carcinoma at the Era of Targeted Therapies.

Gastric and gastro-esophageal cancers (GC/GEJ) appear as the second cancer-related death worldwide. Diagnosis is made at an advanced stage offering a curative attempt in less than 50% of cases. Despite the improvements of the systemic cytotoxic chemotherapy regimens, the prognosis of patients with metastatic GC/GEJ cancer remains poor.

White Dwarfs in Cataclysmic Variables: An Update.

In this review, we summarize what is currently known about the surface temperatures of accreting white dwarfs in non-magnetic and magnetic cataclysmic variables (CVs) based upon synthetic spectral analyses of far ultraviolet data. We focus only on white dwarf surface temperatures, since in the area of chemical abundances, rotation rates, WD masses and accretion rates, relatively little has changed since our last review, pending the results of a large HST GO program involving 48 CVs of different CV types. The surface temperature of the white dwarf in SS Cygni is re-examined in the light of its revised distance.

FAR ULTRAVIOLET SPECTROSCOPY OF THE RECURRENT NOVA T PYXIDIS.

With six recorded nova outbursts, the prototypical recurrent nova T Pyxidis (T Pyx) is the ideal cataclysmic variable system to assess the net change of the white dwarf mass within a nova cycle. Recent estimates of the mass ejected in the 2011 outburst ranged from a few ~10 to 3.3 × 10, and assuming a mass accretion rate of 10-10 yr for 44 yr, it has been concluded that the white dwarf in T Pyx is actually losing mass.

[Muscle-tendon echography in acute cervical sprain traumas. Preliminary results].

Acute cervical sprain traumas can be divided into simple and severe, depending on the presence of organic lesions which can be documented by conventional radiologic techniques. Persistent painful symptomatology of the nape and the precise localization of pain, led us to suspect the presence of organic lesions due to tearing of the neck muscles in 94 patients who had suffered a simple cervical sprain. To demonstrate these post-traumatic lesions, the patients were subjected to US examinations of both the nape and the muscles at the base of the neck.