Publications by authors named "Sinuo Liu"

Meshless simulation of elasticity is important for deformable simulation in computer graphics. While shape matching is a popular meshless solution, it is limited to a subset of elastic constitutive models, challenging the simulation of generic elastic constitutive models using meshless integration. In contrast, peridynamics offers a more versatile capacity and can describe various material behavior through non-local interactions between vertices.

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The cleavage of sialic acids by neuraminidase (NA) facilitates the spread of influenza A virus (IV) descendants. Understanding the enzymatic activity of NA aids research into the transmission of IVs. An effective method for purifying NA was developed using -aminophenyloxamic acid-modified functionalized hydroxylated magnetic particles (AAMPs), and from 0.

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Ultrasound-modulated optical tomography (UOT), which combines the advantages of both light and ultrasound, is a promising imaging modality for deep-tissue high-resolution imaging. Among existing implementations, camera-based UOT gains huge advances in modulation depth through parallel detection. However, limited by the long exposure time and the slow framerate of modern cameras, the measurement of UOT signals always requires holographic methods with additional reference beams.

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Hydrogen is well known to embrittle high-strength steels and impair their corrosion resistance. One of the most attractive methods to mitigate hydrogen embrittlement employs nanoprecipitates, which are widely used for strengthening, to trap and diffuse hydrogen from enriching at vulnerable locations within the materials. However, the atomic origin of hydrogen-trapping remains elusive, especially in incoherent nanoprecipitates.

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We propose a novel weakly supervised approach for 3D semantic segmentation on volumetric images. Unlike most existing methods that require voxel-wise densely labeled training data, our weakly-supervised CIVA-Net is the first model that only needs image-level class labels as guidance to learn accurate volumetric segmentation. Our model learns from cross-image co-occurrence for integral region generation, and explores inter-voxel affinity relations to predict segmentation with accurate boundaries.

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Motivation: Cryo-Electron Tomography (cryo-ET) is a 3D imaging technology that enables the visualization of subcellular structures in situ at near-atomic resolution. Cellular cryo-ET images help in resolving the structures of macromolecules and determining their spatial relationship in a single cell, which has broad significance in cell and structural biology. Subtomogram classification and recognition constitute a primary step in the systematic recovery of these macromolecular structures.

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Background: Cryo-electron tomography is an important and powerful technique to explore the structure, abundance, and location of ultrastructure in a near-native state. It contains detailed information of all macromolecular complexes in a sample cell. However, due to the compact and crowded status, the missing edge effect, and low signal to noise ratio (SNR), it is extremely challenging to recover such information with existing image processing methods.

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Water conservation and soil retention are two essential regulating services that are closely related, and their relationship might produce synergies or trade-offs. Distinguishing the current status and evolution of research in this field could provide a scientific foundation for subsequent research. "Water conservation" and "soil retention" were selected as keywords for a search of Web of Science for publications during 1976-2018.

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Joint sealant is affected by various environmental factors in service, such as different temperatures, water soaking, ultraviolet and so on. In this paper, the VAE emulsion-cement compositejoint sealant was pretreated under multiple simulation environments. Thereafter, the degradation rules of fixed elongation and tensile properties of joint sealants at different mix proportions were systemically investigated under the action of external environments (temperature, water soaking and ultraviolet), and the influence mechanisms of diverse environmental factors were analyzed.

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Article Synopsis
  • The study investigates the origin of metazoan larvae, analyzing two main hypotheses: 'larva-first' (early metazoans were like larvae) and 'adult-first' (early metazoans were adults with larvae evolving later).
  • Researchers focused on mollusks, known for their trochophore larvae, and found that these larvae have rapidly evolving transcriptomes and novel genes linked to shell development.
  • The analysis suggests support for the 'adult-first' hypothesis, indicating that proto-larvae likely appeared after Ctenophora diverged from a common ancestor with other metazoans.
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The major causal factors for the irreversible decline in physical vitality during organismal aging are postulated to be a chronic state of cellular redox imbalance, metabolic toxicity, and impaired energy homeostasis. We assessed whether the relevant enzyme activity, oxidative stress, and intracellular ATP might be causally involved in the aging of short-lived Chlamys farreri (life span 4~5 years). A total of eight related biochemical and cellular indicators were chosen for the subsequent analysis.

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Cellular signaling initiated by various secreted, cysteine-rich Wnt proteins plays essential roles in regulating animal development and cell stemness. By virtue of its functional diversity and importance, the Wnt gene family has received substantial research interests in a variety of animal species, from invertebrates to vertebrates. However, for bivalve molluscs, one of the ancient bilaterian groups with high morphological diversity, systematic identification and analysis of the Wnt gene family remain lacking.

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