Sustained release local anesthetics for pain management: relevance and formulation approaches.

This review attempted to ascertain the rationale for the formulation of sustained-release local anesthetics and summarize the various formulation approaches designed to date to achieve sustained and localized local analgesic effects. The incidence of pain, which is the concern of patients as well as health care professionals, is increasing due to accidents, surgical procedures, and other diseases. Local anesthetics can be used for the management of moderate to severe acute and chronic pain.

Commentary: Nanoparticle-Based Chemotherapy Delivery and Potential Health Risks: Prospects for Effective Clinical Translation.

With recent advancements, chemotherapy is one of the most prevalent regimens for cancer treatment. However, the heterogeneity of tumor biology and healthy cell-damaging potential of chemotherapy remain challenges. As a solution, nanoparticle-based delivery is advancing.

Extent and barriers to providing effective pharmaceutical compounding services in hospital and community pharmacies of a low-income country: Case of Southwest Ethiopia.

Background And Objective: In low- and middle-income countries, pharmaceutical compounding is vital to provide high-quality healthcare service. Accordingly, this study aimed to investigate the extent status of practice and barriers to compounding services in hospital and community pharmacies of Southwest Ethiopia.

Methods: A healthcare institution-based cross-sectional study was conducted from 15 September 2021 to 25 January 2022.

Medication counselling practices amid COVID -19 pandemic and associated factors in drug retail outlets of Jimma town, Southwest Ethiopia: cross-sectional study.

Background: Patients' good understanding and awareness of drug information received at the drug retail outlet is paramount to gaining expected outcomes. In the COVID-19 pandemic, the routine counselling practice faced multifactorial challenges.

Objectives: The study aimed to assess medication counseling practice and associated factors in drug retail outlets of Jimma town, southwest Ethiopia.

Knowledge and attitudes toward euthanasia among final year pharmacy and law students: a cross-sectional study.

Background: Euthanasia is the last resort for those living with untreatable and terminable diseases which cause pain and suffering. However, the concept of euthanasia resulted in many dilemmas and controversy around life extension and death.

Objective: The aim of this study was to evaluate the knowledge and attitudes of final year pharmacy and law students concerning euthanasia.

An analysis of COVID-19 information sources.

Background: The COVID-19 pandemic has brought new situations that require the effective delivery of health information across the world and it's important to offer clear, consistent, and credible information on the pandemic to mitigate and control the outbreak.

Aim: To assess COVID-19 information source, need and trust among the rural community of southwest Ethiopia.

Methods: A community-based cross-sectional study design was conducted among 634 rural communities of southwest Ethiopia.

Generic substitution for prescribed brand medicines in Ethiopia: knowledge, attitude and practice among pharmacy professionals in community drug retail outlets.

Background: Generic substitution is a good approach to reduce pharmaceutical expenses without compromising healthcare quality. Yet, the practice of generic substitution has been contentious due to concerns on quality and efficacy.

Objective: This study was aimed to assess knowledge, attitude and practice among pharmacy professionals toward generic substitution in community drug retail outlets in Jimma town, Southwest Ethiopia.

Investigating the knowledge, perception, and practice of healthcare practitioners toward rational use of compounded medications and its contribution to antimicrobial resistance: a cross-sectional study.

Background: Pharmaceutical compounding ensures access of individuals with specific requirements to individualized therapy. However, there is an inconsistency of compounded medication quality. Therefore, advancing the rational use of compounded medication is essential for patient safety and medication effectiveness.

Traditional Medicine Practice in the Context of COVID-19 Pandemic: Community Claim in Jimma Zone, Oromia, Ethiopia.

Purpose: To assess traditional medicine practice claims by the community for the prevention and treatment of COVID-19.

Methods: A community-based cross-sectional study design was conducted among 422 households of Jimma Zone, and the data were collected by interviewing individuals from the selected households. The medicinal plants were recorded on Microsoft excel 2010 with their parts used, dosage form, route of administration and source of plants and tabulated in the table.

Knowledge, Attitude and Self-Reported Performance and Challenges of Hand Hygiene Using Alcohol-Based Hand Sanitizers Among Healthcare Workers During COVID-19 Pandemic at a Tertiary Hospital: A Cross-Sectional Study.

Background And Objective: Understanding and consistent hand hygiene practice by alcohol-based hand sanitizer is a cardinal step to stay safe from the coronavirus disease (COVID-19) pandemic. This study aimed to assess the self-reported level of knowledge, attitude, practice, and challenges to practice hand hygiene by alcohol-based hand sanitizers among healthcare workers during the COVID-19 pandemic in Jimma Medical Center, Ethiopia.

Methods: Between April and June 2020, a questionnaire-based descriptive cross-sectional study was conducted using 96 study participants.