[Estimation of central blood pressure and arterial stiffness in pregnant women with different forms of hypertension].

Aim: To estimate central (aortic) blood pressure (BP) and arterial stiffness and their prognostic value in the development of preeclampsia (PE) in pregnant women with different forms of hypertension.

Subjects And Methods: The study included 106 patients with chronic hypertension, 21 with the latter concurrent with PE, 63 with gestational hypertension, 10 with PE, and 100 without hypertension. All the women underwent 24-hour BP monitoring by an oscillometric method to estimatecentral (aortic) BP and arterial stiffness at 16-22 weeks' gestation.

[Clinical-anamnestic and molecular-genetic factors in different forms of hypertension and its relationship to course and pregnancy outcomes].

Aim: To assess of the relationship of clinical and molecular genetic factors in the course and outcome of pregnancy in different forms of hypertension in pregnant women.

Patients And Methods: A total of 125 pregnant women who were divided into the following groups: with chronic hypertension (n = 45), with gestational hypertension (n = 20), with pre-eclampsia (n = 10), superimposed preeclampsia upon chronic hypertension (n = 15) and 35 women without hypertension in control group.

Results: In pregnant women with chronic hypertension and superimposed preeclampsia upon chronic hypertension were observed higher incidence of overweight and obesity, smoking before pregnancy and family history of hypertension and thrombosis, the course and outcomes of pregnancy characterized by higher frequency of obstetric complications, higher frequency of polymorphisms of genes identified the renin-angiotensin system, folate cycle and endothelial function.

[The method of replacement of defects in impression fractures of calcaneus. Porous NiTi or autotransplant?].

An experience with treatment of 149 patients with severe injuries of the ankle joint operated using constructions of titanium-nickelide and autotransplant from the iliac crest is presented. Porous NiTi being bio-inert to organism tissues, having high through porosity, the formation of consolidation of the fracture develops more rapidly. Application of porous NiTi allowed the period of disablement to be on an average 20 days shorter and long-term results to be reliably better.

[The dynamics of indicators of hemostasis in case of physiologically progressing pregnancy].

The conditions of vascular thrombocyte, coagulator and fibrinolytic components of hemostasis were evaluated in trimestral dynamics in 65 healthy pregnant women without thrombotic risk factors and with physiologically progressing pregnancy resulted in timely delivery of term fetus. In the process of gestation, the increase of spontaneous and induced aggregative activity of thrombocytes, the increase of levels of fibrinogen, soluble fibrin monomeric complexes. D-dimer and fibrinolysis delay were established.

Tolerance to antimicrobial agents and persistence of Escherichia coli and cyanobacteria.

Bacterial persistence is the tolerance of a small part of a cell population to bactericidal agents, which is attained by a suppression of important cell functions and subsequent deceleration or cessation of cell division. The growth rate is the decisive factor in the transition of the cells to the persister state. A comparative study of quickly growing Escherichia coli K-12 strain MC 4100 and cyanobacteria Synechocystis sp.

[Lactate biosensor and energy supply for the enzyme molecule].

A biosensor of lactate has been constructed, made, and tested. The lactate biosensor uses the lactate dehydrogenase molecules from muscle. The lactate biosensor works according to the simplest scheme.

H2O2 intensifies CN(-)-induced apoptosis in pea leaves.

H2O2 intensifies CN(-)-induced apoptosis in stoma guard cells and to lesser degree in basic epidermal cells in peels of the lower epidermis isolated from pea leaves. The maximum effect of H2O2 on guard cells was observed at 10(-4) M. By switching on non-cyclic electron transfer in chloroplasts menadione and methyl viologen intensified H2O2 generation in the light, but prevented the CN--induced apoptosis in guard cells.

H2O2-induced inhibition of photosynthetic O2 evolution by Anabaena variabilis cells.

Hydrogen peroxide inhibits photosynthetic O2 evolution. It has been shown that H2O2 destroys the function of the oxygen-evolving complex (OEC) in some chloroplast and Photosystem (PS) II preparations causing release of manganese from the OEC. In other preparations, H2O2 did not cause or caused only insignificant release of manganese.

[Activation of GABA system metabolism in the cerebral hemispheres during exposure to different stress factors].

The paper concerns the basic parameters of GABA metabolism in 4 groups of animals: after emotional pain stress; after twofold administration of formalin; after coronary artery ligation; after narrowing of the aorta ostium. GABA metabolism in all brain systems was shown to be activated in all types of exposure to stress. One of the final GABA metabolites, hydroxybutyric acid, prevents undue enhancement of pituitary-adrenal function and injury to the internal organs during stress.