Publications by authors named "Sinisa Trbovic"

Psychosis and dreaming have many similarities, including delusions, hallucinations, bizarre thinking and perceptual distortions. This clinical observation has lead us to hypothesize that the suprachiasmatic nucleus (SCN), a hypothalamic center regulating sleep and wakefulness, is involved in the pathogenesis of schizophrenia. Schizophrenic patients have certain sleep architecture characteristics, and distinctive biological markers suggesting abnormity of the SCN, including irregular pattern of melatonin secretion, abnormal actigraphyic studies, D1-dopamine receptors involvement in the process of entraining the SCN and vulnerability to psychotic exacerbation due to jet lag.

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Here we show the first example of in vivo oxygen-17 (17O) magnetic resonance imaging of the human in natural abundance. Two-dimensional fast multi-planar gradient recalled 90 deg echo (FMPGR/90) pulse sequence and three-dimensional projection reconstruction pulse sequence methods were used.

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