Publications by authors named "Sinhye Kim"
Efficacy and safety of biosimilar trastuzumab (CT-P6) in routine clinical practice in the Republic of Korea: a real-world post-marketing surveillance study.
Expert Opin Biol Ther
April 2024
Article Synopsis
- CT-P6, a biosimilar for trastuzumab, is approved for treating HER2-positive early breast cancer, metastatic breast cancer, and metastatic gastric cancer.
- A 1-year post-marketing surveillance study in South Korea evaluated its safety and effectiveness, involving 642 patients treated with CT-P6.
- Results showed that while over half of the patients experienced adverse events, the majority did not indicate new safety concerns, and notable responses were observed in a significant portion of trastuzumab-naïve patients.
Background: The COVID-19 pandemic radically changed nursing education.
Purpose: To map the existing literature on learning environments (LEs) in undergraduate nursing education during COVID-19 and identify the LE elements based on the 4 domains of Gruppen's conceptual framework: personal, social, organizational, and physical and virtual spaces.
Method: Eligible articles were reviewed using the Joanna Briggs framework.
Background: Registered nurse (RN) turnover is a recurring phenomenon that accelerated during COVID-19 and heightened concerns about contributing factors.
Purpose: Provide baseline RN turnover data to which pandemic and future RN workforce turnover behaviors can be compared.
Methods: A cross-sectional, secondary analysis of RN turnover using U.
Patient Safety Culture: The Impact on Workplace Violence and Health Worker Burnout.
Workplace Health Saf
February 2023
Background: Patient and health care worker safety is an interconnected phenomenon. To date, few studies have examined the relationship between patient and worker safety, specifically with respect to work safety culture. Therefore, we examined patient safety culture, workplace violence (WPV), and burnout in health care workers to identify whether patient safety culture factors influence worker burnout and WPV.
View Article and Find Full Text PDFBackground: Workplace violence (WPV) against nurses has a negative impact on the nurses and the care they provide. Formal reporting of WPV is necessary to understand the nature of violent incidents, develop proactive coping strategies, and provide support for nurses affected by WPV.
Purpose: This study explored the relationships among nurses' WPV experiences, burnout, patient safety, and the moderating effect of WPV-reporting culture on these relationships.
Background: The rising rate of workplace violence in hospitals is a serious concern. While leading organisations recommend implementing interventions to address workplace violence, little is known about the workplace violence relationship between patients and visitors, and how it affects nurses' emotional exhaustion and their perceptions of patient safety.
Aims: The study's purpose was to understand the status of workplace violence in hospitals and the relationships between nurses' experiences of workplace violence, emotional exhaustion, and perceptions of patient safety.
Background: CT-P16 is a candidate biosimilar of bevacizumab, a monoclonal antibody targeting vascular endothelial growth factor that is used in the treatment of a range of advanced solid cancers.
Objective: The objective of this study was to demonstrate the pharmacokinetic equivalence of CT-P16 and European Union (EU)-approved bevacizumab (EU-bevacizumab) and US-licensed bevacizumab (US-bevacizumab) reference products.
Methods: In this double-blind, parallel-group phase I trial (ClinicalTrials.
Objective: The purpose of this study was to explore the association of nurse staffing and overtime with nurse-perceived patient safety, nurse-perceived quality of care, and care left undone.
Design: A cross-sectional survey.
Setting And Participants: A total of 65 hospitals were selected from all of the acute hospitals (n=295) with 100 or more beds in South Korea by using a stratified random sampling method based on region and number of beds, and 60 hospitals participated in the study.
Purpose: The purpose of this study was to examine the relationships of nurse staffing level and work environment with patient adverse events.
Design: This cross-sectional study used a combination of nurse survey data (N = 4,864 nurses), facility data (N = 58 hospitals), and patient hospital discharge data (N = 113,426 patients) in South Korea.
Methods: The three most commonly nurse-reported adverse events included administration of the wrong medication or dose to a patient, pressure ulcers, and injury from a fall after admission.
Objective: Korea introduced universal long-term care insurance (LTCI) for physically dependent older adults in 2008. Older adults, their family members, and policy makers in Korea want to know patient outcomes in different care modalities because older adults who have a similar functional status and LTC needs can choose either nursing home care or home care. The aim of this study was to compare activities of daily living (ADLs) in nursing home care and home care settings for physically dependent older adults in Korea.
View Article and Find Full Text PDFPurpose: The aim of this study was to assess the suitability and readability of printed educational materials for patients with hypertension in Korea.
Methods: A total of 33 written educational materials related to hypertension were collected from public health centers, hospitals, and internet web site. Among them, we analyzed 19 materials which fit the inclusion criteria: leaflets (n=9), booklets (n=3), and guide book (n=7).