Publications by authors named "Singh Prit"

Background: Chronic kidney disease (CKD) is a global public health burden with significantly increasing mortality. Chronic kidney disease leads to various complications, including anemia, cardiovascular complications, salt and water retention, metabolic acidosis, electrolyte disorders, and chronic kidney disease-mineral and bone disorder (CKD-MBD), amongst which CKD-MBD is a particularly important complication that develops early.

Materials And Methods: In the present study, various biochemical analytes were assessed for their significance in monitoring the CKD-MBD in different stages of CKD.

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  • - Myoglobin cast nephropathy occurs after rhabdomyolysis, leading to myoglobin release that damages kidney tubules and causes blockages.
  • - The case discussed involves a patient taking neuroleptic drugs who developed neuroleptic malignant syndrome, a serious reaction often caused by these medications.
  • - This patient also experienced acute kidney injury due to the complications from myoglobin cast nephropathy related to their condition.
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  • - Insertion of a peritoneal dialysis (PD) catheter in patients with end-stage renal disease (ESRD) and liver cirrhosis is difficult, often leading to complications like ascitic fluid leaks that disqualify them from PD.
  • - A case study involving three ESRD patients with tense ascites who underwent large volume fluid drainage alongside hemodialysis found that they had a challenging lifestyle due to multiple medical procedures each week.
  • - To prevent leaks after PD catheter insertion, the study suggests using a continuous drainage system for about two weeks post-surgery before beginning PD training, which resulted in successful healing without complications.
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  • Chronic kidney disease (CKD) is a global health issue, particularly concerning in Bihar, India, where it frequently coexists with conditions like type 2 diabetes, hypertension, and cardiovascular diseases, complicating patient outcomes.
  • A study involving 2,534 adult patients in Patna revealed that a significant portion of CKD patients were young males from rural areas, with hypertension and chronic tubulointerstitial nephritis being the leading causes.
  • The study identified poor management practices regarding the use of standard treatments and highlighted the pressing need for better treatment strategies to slow kidney function decline in this population.
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  • Pigment-induced acute kidney injury (AKI) occurs when harmful pigments from myoglobin or hemoglobin cause damage to the kidneys, often linked to conditions like rhabdomyolysis or hemolysis.
  • The study reports eight cases of pigment-induced AKI, primarily from myoglobin and hemoglobin casts, triggered by factors such as intense exercise, infections, or certain medications.
  • While most patients required dialysis initially, their short-term kidney recovery was positive, highlighting the need for ongoing monitoring to check for potential long-term effects.
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Background: There is a lack of standardized treatments for patients with less than 50% crescents observed in their renal biopsies. This study aimed to analyze the crescent percentage, clinicopathological characteristics, and renal prognosis of glomerulonephritis (GN) cases with at least one crescentic lesion.

Materials And Methods: This retrospective cohort study was conducted at the Indira Gandhi Institute of Medical Sciences, Patna, from January 2016 to December 2020.

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Acute and chronic noncancer pain is a common healthcare problem locally and globally, and remains under treated and poorly controlled. We created a virtual reality (VR)-based prototype with customization of content to our local population. This was an open-label, single center, single-arm study to examine the safety, acceptability and tolerability of the use of VR as an adjunctive tool for pain relief in hospitalized patients.

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Background: Nephrotic syndrome (NS) is characterized by various clinicopathological conditions like proteinuria, hypoalbuminemia, and anasarca. Patients with NS are prone to experience associated problems like acute kidney injury (AKI). The present study aimed to investigate the clinical profile and outcomes of NS with AKI in adults.

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The present study portrays a facile, cost-effective, and environmentally benign way for the preparation of TiO nanoparticles utilizing C. limon extract, which possesses phytochemicals as reducing and stabilizing agents. Structural characterization by XRD reveals that C.

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Aquatic ecology has been greatly threatened by the discharge of effluents of textile and antibiotic industries into natural waters. Herein, an efficient and easily recycled reduced graphene oxide/zirconium oxide nanocomposite has been synthesized using banana peel extract (abbreviated as rGO-ZrO in this work). The X-ray diffraction (XRD), field emission scanning electronic microscopy (FESEM), high-resolution transmission electron microscopy (HRTEM), Brunauer-Emmett-Teller (BET), UV-visible diffuse reflectance spectroscopy (DRS), X-ray photoelectron spectroscopy (XPS), and Fourier transform infrared (FTIR) spectroscopy were used to analyze the synthesized material.

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Various vaccines against coronavirus disease 2019 (COVID-19) have been developed amidst the ongoing pandemic. Few cases of glomerulonephritis after COVID-19 vaccination have been reported globally. We present a case of nephrotic syndrome due to minimal change disease (MCD) most likely associated with the ChAdOx1 nCoV-19 vaccine.

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Introduction: COVID-19 in kidney transplant recipients (KTR) had been associated with high incidence of acute kidney injury and higher mortality. Management of these patients is still evolving.

Methods: A retrospective observational study was done that included all KTR aged ≥18 years and ≤65 years who had COVID-19 diagnosis via RTPCR test between 1 June 2020 and 30 May 2021.

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Tetracycline (TC) is a frequently administered antibiotic in many countries, due to its low price and excellent potency. However, certain antibiotics can be hazardous to living creatures due to their accumulation by complexation with metal ions which can contribute to teratogenicity and carcinogenicity. In this investigation, copper oxide-ferric oxide nanocomposite (CuO/FeO nanocomposite) was synthesized employing Psidium guajava (P.

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The present work encompasses a simple strategy to synthesize highly porous TiO by incorporating PANI polymer into the sol-gel chemistry of Titanium dioxide/Titanium (IV)-iso-propoxide (TiO/TTIP). A series of TiO samples by varying wt.% of PANI, have been synthesized.

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In the field of photocatalysis, fabrication of a heterojunction structure with effective charge separation at the interface and charge shift to enhance the photocatalytic activity has acquired extensive consideration. In the present investigation, MnVO/BiVO heterojunction samples with excellent photocatalytic performance under sunlight irradiation were conveniently synthesized by a hydrothermal technique, and characterized by UV-Vis, FTIR, XRD, FESEM, HRTEM, PL, BET and XPS techniques. The prepared samples were investigated as photocatalysts for degrading MB and RhB dyes under sunlight.

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Obesity is no longer a disease of the affluent. The prevalence of obesity has risen at an exponential rate globally, with an increasing burden on healthcare resources. Perioperative management of patients with morbid obesity is known to be challenging, and this is particularly so in the management of their airway, a crucial procedure that requires meticulous planning and modifications.

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The coronavirus disease 2019 (COVID-19) led to a global pandemic which is still unfolding. Little is known about the presentation, course of disease, treatment, and outcome in kidney transplant recipients. In this series, we describe nine such patients who presented with COVID-19.

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Purpose: To compare the efficacy of High flow nasal cannula (HFNC) as an alternative to Continuous Positive Airway Pressure (CPAP) therapy on the first postoperative night in patients with suspected moderate to severe obstructive sleep apnea (OSA).

Methods: This is randomised controlled trial conducted in a tertiary hospital which included elective surgical patients with STOP-BANG score of 5 and above. Forty patients were randomised into one of the four postoperative treatment groups: CPAP, or HFNC at three different flow rates (20 L/min, 30 L/min and 40 L/min).

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Kidney paired donation is the most cost-effective approach in incompatible donor-recipient pairs. Incompatibility may be due to blood group, human leucocyte antigen crossmatch or both. In many cases of a living donor kidney transplant, there is only one potential donor who becomes unsuitable due to any of the above mentioned factors.

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Introduction: Prolonged surgery is a known risk of pressure ulcer formation. Pressure ulcers affect the quality of life, are a significant cause of morbidity and mortality, and pose a burden on the healthcare system. This study aimed to compare the effectiveness of an alternating pressure (AP) overlay with Gel pad against the Gel pad in reducing interface pressure (IP) during prolonged surgery.

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Purpose: Education in airway management is a fundamental component of anesthesiology training programs. There has been a shift towards the use of simulation models of higher fidelity for education in airway management. The goal of this study was to create a novel cadaveric model of a simulated parapharyngeal abscess with features of a difficult airway such as distorted anatomy and narrow airway passages presenting as stridor.

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Heavy metal ions and pesticides are the noteworthy toxic substances which must be removed from contaminated water for safeguarding public health. The higher levels of these substances in natural water may adversely affect the human health, climate and the eco-framework. The adsorptive removal of hazardous constituents employing metal organic frameworks has drawn considerable attention of researchers during the last decade.

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Background: Chronic non-cancer pain affects about 20% of the population worldwide. The effect of medical treatment in isolation is often limited. A multidisciplinary approach has been strongly advocated to help manage patients' pain more effectively.

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