Background: Malnutrition screening is not widely practiced in outpatient cancer centers. This review aims to determine the validity of malnutrition screening tools and provide recommendations for clinical use.
Methods: Studies identified by a systematic review assessed the general validity of screening tools in adult oncology outpatients from five databases through 2022.
The efficacy of Ozonated oil in treating chronic periodontitis compared to Chlorhexidine gel following Scaling and Root Planing (SRP) is of interest. Fifty-six patients were randomly assigned to two groups: one receiving Ozonated oil post-SRP and the other receiving Chlorhexidine gel. Periodontal indices (Plaque Index, Gingival Index), Periodontal Probing Depth (PPD), and Clinical Attachment Level (CAL) were measured at baseline, one month, and three months.
View Article and Find Full Text PDFElephantiasis, also known as filariasis, is a severe public health issue in India. Microfilariae in the bone marrow smears are an unusual and incidental finding. Every peripheral blood and bone marrow aspirate smear must be screened for microfilariae in endemic areas to identify asymptomatic carriers.
View Article and Find Full Text PDFThe effect of chitooligosaccharide-EGCG conjugate (CEC) at different concentrations (0, 1, and 2%; /) and depuration times (DT; 3, and 6 h) on the total viable count and spp. count of Asian green mussels (AGMs) was studied. Depurated samples showed a reduction in both microbial counts as compared to fresh AGMs (without depuration) and AGMs depurated using water (CON).
View Article and Find Full Text PDFThe landscape of clinical management for metastatic melanoma (MM) and other solid tumors has been modernized by the advent of immune checkpoint inhibitors (ICI), including programmed cell death-1 (PD-1), programmed cell death-ligand 1 (PD-L1), and cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibitors. While these agents demonstrate efficacy in suppressing tumor growth, they also lead to immune-related adverse events (irAEs), resulting in the exacerbation of autoimmune diseases such as rheumatoid arthritis (RA), ulcerative colitis (UC), and Crohn's disease (CD). The immune checkpoint inhibitors offer promising advancements in the treatment of melanoma and other cancers, but they also present significant challenges related to irAEs and autoimmune diseases.
View Article and Find Full Text PDFThe objective of this study was to examine the interactions between anionic surfactants, specifically 1-alkylsulfonates (KXS) and 1-alkylsulfates (SXS) ions, with human serum albumin (HSA). A combination of experimental techniques, including isothermal titration calorimetry (ITC), steady-state fluorescence spectroscopy (SF), and molecular dynamics-based approaches was employed to gain a comprehensive understanding of these processes. It has been demonstrated that the subtle variations in the charge distribution on the anionic surfactant headgroups have a significant impact on the number of binding sites, the stoichiometry of the resulting complexes, and the strength of the interactions between the surfactants and the protein.
View Article and Find Full Text PDFWe theoretically examine the spatiotemporal evolution of near-field optical chirality (OC) in both plasmonic and dielectric nanospheres when excited by ultrashort optical pulses. We demonstrate distinct spatiotemporal variations in the near-field OC arising from the differing natures of plasmonic and dielectric resonators. The electric dipole resonant plasmonic nanosphere generates an instantaneous near-field OC that relies on the interference between incident and scattered (induced) fields.
View Article and Find Full Text PDFThe present study aims to develop, optimize and assess hispolon (HPN) lipid nanocapsules (LNCs), solid lipid nanoparticles (SLNs) and suspension for treating hepatocellular carcinoma (HCC). It included UPLC-MS/MS, solubility, optimization, characterization, stability, and studies. HPN-loaded LNCs were developed using phase-inversion and temperature cycling, while SLNs and suspension using hot homogenization and trituration methods.
View Article and Find Full Text PDFThis research aims to address common constraints in the effective utilization of plant nutrients in soil, such as fixation, mobility, leaching, and reactions with soil colloids. To mitigate these issues, Fe and Zn citrate nanoparticles were synthesized and applied as nanochelators in a reconstructed soil profile column. We evaluated the mobility, release, and leaching behaviors of these nanoparticles.
View Article and Find Full Text PDFType 2 diabetes mellitus (T2DM), responsible for most diabetes cases recorded worldwide, increases the risk of chronic wounds and amputation. Patients with T2DM appear to be more susceptible to delayed wound healing due to their treatment adherence. This review explores the specifics of polypharmacy, side effects, possible drug interactions and the importance of medication adherence for therapeutic efficacy.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
October 2024
Background: Understanding the geographic variation of unintended pregnancy is crucial for informing tailored policies and programs to improve maternal and child health outcomes. Although spatial analyses of unintended pregnancy have been conducted in several developing countries, such research is lacking in India. This study addresses this gap by investigating the geographic distribution and determinants of unintended pregnancy in India.
View Article and Find Full Text PDFThe immune system, a central player in maintaining homeostasis, emerges as a pivotal factor in the pathogenesis and progression of two seemingly disparate yet interconnected categories of diseases: autoimmunity and cancer. This chapter delves into the intricate and multifaceted role of the immune system, particularly T cells, in orchestrating responses that govern the delicate balance between immune surveillance and self-tolerance. T cells, pivotal immune system components, play a central role in both diseases.
View Article and Find Full Text PDFIndonesia generates approximately 7.8 million tons of plastic waste annually, which 4.9 million tons is mismanaged.
View Article and Find Full Text PDFPhase separation within cellular membranes, a critical process underpinning diverse cellular functions, is significantly influenced by transmembrane proteins. Therefore, elucidating the behavior of a transmembrane protein in its phase-separated state is of utmost importance. Our study explores mucin behavior in the cellular milieu, aiming to determine the role of crowder chain length and excluded volume in phase separation.
View Article and Find Full Text PDFPrisma Hand II is an under-actuated prosthetic hand developed at the University of Naples, Federico II to study in-hand manipulations during grasping activities. 3 motors equipped on the robotic hand drive 19 joints using elastic tendons. The operations of the hand are achieved by combining tactile hand sensing with under-actuation capabilities.
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