Publications by authors named "Sinem Gungor"

Article Synopsis
  • Pulmonary endarterectomy is a surgical option for chronic thromboembolic pulmonary hypertension (CTEPH) that can potentially cure the condition, and this study looked at factors influencing patient outcomes post-surgery.
  • The study analyzed data from 834 patients who underwent surgery between March 2014 and January 2024, revealing a 7.8% in-hospital mortality rate and highlighting that older patients (≥70 years) had a significantly higher mortality rate compared to younger patients (<70 years).
  • Key predictors of mortality included age, length of ICU stay, the Charlson Comorbidity Index, and six-minute walk distance, with the findings indicating that while elderly patients faced higher risks, the surgery could still lead
View Article and Find Full Text PDF

Objective:  Coronavirus disease 2019 (COVID-19) caused morbidity and mortality worldwide. Besides the acute effects, subacute and long-term effects are defined as long-COVID causing morbidity. The intensive care unit (ICU) data of long-COVID-19 cases were evaluated with the participation of 11 centers.

View Article and Find Full Text PDF

Objective: A 1-day point prevalence study was planned to obtain country data by determining the clinical characteristics, follow-up and treatment methods of coronavirus disease 2019 (COVID-19) cases that required intensive care unit (ICU) treatment in the second year of the pandemic.

Material And Methods: All patients who were hospitalized in the ICUs due to COVID-19 between March 11, 2022, 08.00 am, and March 12, 2022, 08.

View Article and Find Full Text PDF

Objective: To evaluate the utility of neutrophil-lymphocyte ratio (NLR) determined at initial diagnosis in predicting advanced disease stage and discriminating between active and stable disease in sarcoidosis.

Methods: A total of 465 patients with biopsy-proven sarcoidosis (age: 47 years, 70.5% females) were included in this retrospective cross-sectional study.

View Article and Find Full Text PDF

Objective: This study aimed to evaluate the prognostic value of inflammatory markers determined during admission among patients with sarcoidosis with chronic and remission groups.

Methods: This study was designed as retrospective single-center study. Patients with sarcoidosis without treatment and who had at least two years of follow-up were included in this study.

View Article and Find Full Text PDF

Background: Elevated red blood cell distribution width (RDW) levels were associated with mortality in patients with stable chronic obstructive lung pulmonary diseases (COPD). There are limited data about RDW levels in acute exacerbation of COPD (AECOPD).

Aim/objective: The association of the RDW levels with the severity of AECOPD was evaluated according to admission location, (outpatient-clinic, ward and intensive care unit (ICU)).

View Article and Find Full Text PDF

Background-aim: Noninvasive mechanical ventilation (NIV) failure rate is reported to be 5%-60% of intensive care unit (ICU) patients. Despite all precautions and well-known reasons, the risk factors of NIV failure are unclear for chronic obstructive pulmonary disease (COPD) with acute respiratory failure (ARF). The aim of this study was to examine risk factors for NIV failure in COPD patients with ARF, other than well defined.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess how gender influences inhaler technique among adults using inhaler therapy and to identify factors that predict correct technique and device changes.
  • It included 568 adults (276 males and 292 females), recording data on demographics, medication, user difficulties, and errors noted by technicians.
  • Results showed that more females reported difficulties with inhalers (63.7% vs 40.6%), and those who received training had significantly better inhaler technique and lower chances of needing a device change.
View Article and Find Full Text PDF

Objectives: The choice of treatment according to the inflammation type in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has been of recent interest. This study investigated the role of novel biomarkers, hospital outcomes, and readmission rates in the first month in patients with eosinophilic or neutrophilic AECOPD.

Materials And Methods: We conducted a retrospective observational cohort study in a Chest Teaching Hospital with hospitalized AECOPD patients.

View Article and Find Full Text PDF

Purpose: This study was designed to evaluate errors in inhaler technique in COPD vs asthma patients and to investigate the association of poor inhaler technique with patient demographics and clinical variables.

Patients And Methods: A total of 509 adult patients with COPD (n=328) or asthma (n=181) who were currently using an inhaler device were included in this study. Data on patient demographics, duration of disease, type and duration of inhaler therapy, and assessment of inhaler technique were recorded.

View Article and Find Full Text PDF
Article Synopsis
  • - Early detection and treatment of infections in patients using non-invasive mechanical ventilation (NIMV) for chronic respiratory failure (CRF) may help lower hospital admissions by assessing inflammatory markers such as CRP, procalcitonin, and NLR.
  • - The study analyzed 49 patients with conditions like COPD, obesity hypoventilation syndrome, and interstitial lung disease, noting characteristics, symptoms, and inflammatory marker levels to compare stable versus acute attack states.
  • - Procalcitonin emerged as a more effective marker for distinguishing acute attacks from stable conditions when compared to CRP and NLR, suggesting its potential role in guiding treatment decisions for patients with chronic inflammatory diseases.
View Article and Find Full Text PDF

Background: Complete blood count parameters provide novel inflammatory markers, namely neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR). We aimed to assess any differences in these novel inflammatory markers according to exacerbation severity in patients with COPD in both eosinophilic and neutrophilic endotypes.

Method: This retrospective cross-sectional study was conducted at a tertiary education hospital.

View Article and Find Full Text PDF

Background: Patients admitted to the intensive care unit (ICU) with acute respiratory failure (ARF) due to COPD have high mortality and morbidity. Acidosis has several harmful effects on hemodynamics and metabolism, and the current knowledge regarding the relationship between respiratory acidosis severity on the short- and long-term survival of COPD patients is limited. We hypothesized that COPD patients with severe acidosis would have a poorer short- and long-term prognosis compared with COPD patients with mild-to-moderate acidosis.

View Article and Find Full Text PDF

Purpose: The aim of this study was to evaluate the impact of exposure to biomass smoke vs cigarette smoke on serum inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure (CRF).

Patients And Methods: A total of 106 patients with CRF divided into age and gender-matched groups of cigarette-smoke exposure (n=55, mean [SD] age: 71.0 [12.

View Article and Find Full Text PDF

Introduction: We aimed to assess the relationship between peripheral eosinophilia and neutrophil/lymphocyte ratio with hospital admissions and re-admissions with chronic obstructive pulmonary disease (COPD) exacerbations.

Materials And Methods: An observational cohort study was carried out in a tertiary teaching hospital. Subjects with previously diagnosed COPD and who were admitted as outpatients with acute exacerbations were included.

View Article and Find Full Text PDF

Aim: Increased dyspnea, sputum volume, and purulence are subjective symptoms in COPD patients. To diagnose COPD exacerbations with chronic respiratory failure (CRF) and to assess the requirement for antibiotic treatment, physicians require more objective criteria. We aimed to investigate whether neutrophil-to-lymphocyte ratio (NLR) can be used as an infectious exacerbation marker in COPD patients with CRF.

View Article and Find Full Text PDF

Objective: While the incidence of sarcoidosis peaks between 20 and 39 years, it is comparatively low in elderly subjects. We sought to determine whether there are age-dependent differences in the demographic and laboratory characteristics of patients with sarcoidosis.

Materials And Methods: We retrospectively collected information from our database using the International Classification of Disease (ICD) diagnostic code D86 between 2008 and 2014.

View Article and Find Full Text PDF

Introduction: Almost 50% of all cancers and 70% of cancer deaths occur in cases aged 65 years and more. Thus diagnosis, treatment and follow up in old cases gain importance. Since there a limited number of study that show age-mortality relation in lung cancer cases aged 80 years and over, issues may arise in diagnosis and treatment process of these cases.

View Article and Find Full Text PDF

BACKGROUND Serum uric acid (sUA) levels were previously found to be correlated with hypoxic states. We aimed to determine the levels of sUA and sUA/creatinine ratios in stable COPD patients and to evaluate whether sUA level and sUA/creatinine ratio can be used as predictors of exacerbation risk and disease severity. MATERIAL AND METHODS This cross-sectional study included stable COPD patients and healthy controls.

View Article and Find Full Text PDF
Article Synopsis
  • Lung cancer is a leading cause of malignant pleural effusions (MPEs), with patients typically experiencing a median survival of only 3-4 months; this study aimed to identify prognostic factors affecting survival in lung cancer patients with MPE.
  • The research analyzed 199 cases of non-small cell lung carcinoma from 2008 to 2011, focusing on demographic and clinical data to estimate survival rates and identify key prognostic indicators.
  • Key findings indicated that elevated serum C-reactive protein, lower serum albumin and pleural protein levels, presence of distant metastasis, and chemotherapy status were significant factors impacting survival outcomes for lung cancer patients with MPEs.
View Article and Find Full Text PDF

Purpose: Noninvasive mechanical ventilation (NIMV) usage outside of intensive care unit is not recommended in patients with COPD for severe acute respiratory failure (ARF). We assessed the factors associated with failure of NIMV in patients with ARF and severe acidosis admitted to the emergency department and followed on respiratory ward.

Patients And Methods: This is a retrospective observational cohort study conducted in a tertiary teaching hospital specialized in chest diseases and thoracic surgery between June 1, 2013 and May 31, 2014.

View Article and Find Full Text PDF

Introduction: Noninvasive ventilation (NIV) during hospitalization for acute hypercapnic exacerbations of chronic obstructive pulmonary disease (COPD) has been shown to be effective, but data on the prognosis of such patients is limited. The aim of this study was to investigate in-hospital and long-term outcome in patients with COPD exacerbations requiring NIV treatment during hospitalization.

Methods: Between 2011 and 2013, hospitalized subjects with hypercapnic COPD exacerbations were included in this retrospective single-center cohort study.

View Article and Find Full Text PDF

Background: COPD exacerbations requiring hospitalization increase morbidity and mortality. Although most COPD exacerbations are neutrophilic, approximately 10%-25% of exacerbations are eosinophilic.

Aim: We aimed to evaluate mortality and outcomes of eosinophilic and non-eosinophilic COPD exacerbations and identify new biomarkers that predict survival.

View Article and Find Full Text PDF

Aim And Background: Currently, there are no objective criteria to determine sarcoidosis activity. The present study aimed to discover a sensitive serum marker that would determine the activity of sarcoidosis and can be used during disease follow-up.

Methods: Forty-eight patients with sarcoidosis and twenty healthy volunteers as a control group were included in the study.

View Article and Find Full Text PDF