Publications by Sindy Gutierrez-Chavarria

Publications by authors named "Sindy Gutierrez-Chavarria"

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ctDNA Is Useful to Detect Mutations at Codon 641 of Exon 16 of EZH2, a Biomarker for Relapse in Patients with Diffuse Large B-Cell Lymphoma.

José Díaz-Chávez Olga Gutiérrez-Hernández Lucia Taja-Chayeb Sindy Gutiérrez-Chavarría Alejandro Avilés-Salas

Cancers (Basel)

September 2022

(1) Background: The epigenetic regulator EZH2 is a subunit of the polycomb repressive complex 2 (PRC2), and methylates H3K27, resulting in transcriptional silencing. It has a critical role in lymphocyte differentiation within the lymph node. Therefore, mutations at this level are implicated in lymphomagenesis.

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