Publications by authors named "Sindhuja Kandasamy"
Article Synopsis
- - Angioid streaks are irregular breaks in Bruch's membrane, appearing as pigmented lines that can indicate underlying systemic diseases like pseudoxanthoma elasticum, Paget's disease, and hemoglobinopathies in about 50% of cases, though some may be idiopathic.
- - Patients often remain asymptomatic until complications arise, such as choroidal neovascular membrane or subretinal hemorrhage, which can occur even from minor trauma due to the membrane's fragility.
- - Diagnosis involves clinical exams and imaging techniques like fundus autofluorescence and optical coherence tomography, while treatment typically focuses on managing complications, often through intravitreal injections of antivascular endothelial growth factor.
A man in his 20s presented with diminished vision in the left eye. He had a history of Pott's spine and had been diagnosed elsewhere as having left eye tubercular granuloma in the retina. He was started on anti-tubercular therapy and high-dose oral steroids.
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- Systemic immunosuppressants and biologicals are useful for treating inflammatory diseases and cancers, but their safety, particularly for localized conditions like eye diseases, is uncertain.
- Alternative local treatments like intravitreal (in the eye), subconjunctival, and topical methods are being explored, especially for patients who can't tolerate standard corticosteroids.
- This review covers the mechanisms, effects, and safety of various intravitreal immunosuppressants and biologicals, noting that most existing research is limited to single cases or small series, reducing the strength of the evidence.
Objectives: To study the thickness of levator palpebra superioris-Muller's muscle complex (LMC) on ultrasound biomicroscopy (UBM) and to correlate with the clinical response to botulinum toxin A (BTA) injection in patients with inactive-stage of thyroid-related upper eyelid retraction (UER). We also studied the correlation of clinical parameters, preinjection with postinjection values.
Methods: This was a prospective, interventional study.