Publications by authors named "Sindhu Richards"

Objective: Delay in referral for epilepsy surgery of patients with drug-resistant epilepsy (DRE) is associated with decreased quality of life, worse surgical outcomes, and increased risk of sudden unexplained death in epilepsy (SUDEP). Understanding the potential causes of delays in referral and treatment is crucial for optimizing the referral and treatment process. We evaluated the treatment intervals, demographics, and clinical characteristics of patients referred for surgical evaluation at our level 4 epilepsy center in the U.

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Purpose: The data resulting from epilepsy surgical evaluation are occasionally unclear in cases of mesial temporal lobe (MTL) epilepsy. Long-term intracranial EEG (iEEG) collected by the Responsive Neurostimulation (RNS) System may be an approach for capturing additional seizure data while treating patients with neurostimulation. We reviewed iEEG seizure lateralization and clinical outcomes in bilateral MTL patients at University of Utah.

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Article Synopsis
  • Burst suppression is a brain state characterized by alternating high and low electrical activity, which can occur due to illness or certain anesthetics, but its variations among individuals have been underexplored.
  • In a clinical trial assessing propofol's antidepressant effects, researchers analyzed EEG data from 21 subjects with treatment-resistant depression, identifying three distinct types of burst activity: broadband bursts, sleep spindle-like activity, and low-frequency bursts (LFBs), each with unique time and frequency traits.
  • The study highlights significant individual differences in the occurrence and spectral makeup of these EEG features, suggesting the need for personalized approaches to anesthetic dosing and revealing limitations in current clinical EEG monitoring systems.
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In high-stake cases (e.g., evaluating surgical candidacy for epilepsy) where neuropsychological evaluation is essential to care, it is important to have culturally and linguistically appropriate and accessible neuropsychological instruments and procedures for use with deaf individuals who use American Sign Language (ASL).

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Epitel has developed Epilog, a miniature, wireless, wearable electroencephalography (EEG) sensor. Four Epilog sensors are combined as part of Epitel's Remote EEG Monitoring platform (REMI) to create 10 channels of EEG for remote patient monitoring. REMI is designed to provide comprehensive spatial EEG recordings that can be administered by non-specialized medical personnel in any medical center.

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