Publications by authors named "Sindhu Chitikela"
Ecancermedicalscience
May 2023
Article Synopsis
- Li Fraumeni syndrome (LFS) is a hereditary cancer risk condition linked to TP53 mutations, with limited research on its impact in the Indian population.
- A study of nine families revealed 29 patients with various cancers, with a notable percentage diagnosed before age 18, underscoring significant childhood cancer risk.
- The study found common cancers like sarcomas and breast cancer, with multiple familial cases, highlighting the importance of genetic testing and early surveillance to catch asymptomatic carriers before cancer develops.
