Publications by authors named "Sinara Figueiredo Silva"
HER2-low status and response to neoadjuvant chemotherapy in HER2 negative early breast cancer.
Luciana de Moura Leite Marcelle Goldner Cesca Monique Celeste Tavares Debora Maciel Santana Erick Figueiredo Saldanha Daniella Dias Silva Sá Sinara Figueiredo Silva Bruna Raphaeli Silva Mattos
Breast Cancer Res Treat
November 2021
Purpose: Knowledge on whether low expressions of HER2 have prognostic impact in early-stage breast cancer (BC) and on its response to current chemotherapy protocols can contribute to medical practice and development of new drugs for this subset of patients, changing treatment paradigms. This study aims to evaluate the impact of HER2-low status on response to neoadjuvant chemotherapy (NACT) and survival outcomes in early-stage HER2-negative BC.
Methods: Records from all BC patients treated with NACT from January 2007 to December 2018 in a single cancer center were retrospectively reviewed.