Publications by authors named "Sinan Sen"

Purpose: Three-dimensional imaging has become an increasingly important component of orthodontics. Associated with this, however, is a higher radiation exposure for patients. New cone-beam computed tomography (CBCT) devices have been developed that can provide low-dose CBCT (LD-CBCT).

View Article and Find Full Text PDF
Article Synopsis
  • The study examined how the experience of examiners affects bone-loss measurements using high-dose (HD) and low-dose (LD) cone beam computed tomography (CBCT) scans.
  • Three diagnosticians with different levels of CBCT interpretation expertise evaluated bone-loss across multiple sites on cadaveric heads, conducting two sets of measurements, with training provided to two diagnosticians in between.
  • Results showed that training improved measurement accuracy and certainty for less experienced diagnosticians, highlighting the important role that examiner experience plays in the reliability of bone-loss assessment using CBCT.
View Article and Find Full Text PDF

Miniscrews offer controlled anchorage and thus optimize tooth movement in orthodontic treatment. Nevertheless, failures such as soft tissue problems, instability due to loosening, partial osseointegration, or even device fracture can occur. While clinical technique can play a role in some of these problems, the manufacturer's design and material choice influence how the implant interacts with the surrounding tissue.

View Article and Find Full Text PDF

Objective: The current study explores whether there is a clinically relevant distinction in the measurement of marginal bone loss when comparing high-dose (HD) versus low-dose (LD) cone beam computed tomography (CBCT) protocols in small and large acquisition volumes.  Material and Methods: CBCTs of four human cadaveric preparates were taken in HD and LD mode in two different fields of view 8 × 8 cm2 (LV) and 5 × 5 cm2 (SV). In total, 43 sites of 15 teeth were randomly chosen, and marginal bone loss was measured twice in all protocols at 43 sites of 15 teeth by one calibrated investigator.

View Article and Find Full Text PDF

Objective: To investigate the image quality of a low-dose dental imaging protocol in the first clinical photon-counting computed tomography (PCCT) system in comparison to a normal-dose acquisition in a digital volume tomography (DVT) system.

Materials And Methods: Clinical PCCT systems offer an increased spatial resolution compared to previous generations of clinical systems. Their spatial resolution is in the order of dental DVT systems.

View Article and Find Full Text PDF

During orthodontic tooth movement, mechanically induced remodeling occurs in the alveolar bone due to the action of orthodontic forces. The number of factors identified to be involved in mechanically induced bone remodeling is growing steadily. With the uncovering of the functions of neuronal guidance molecules (NGMs) for skeletal development as well as for bone homeostasis, NGMs are now also among the potentially significant factors for the regulation of bone remodeling during orthodontic tooth movement.

View Article and Find Full Text PDF

Clinical photon-counting CT (PCCT) offers a spatial resolution of about 200 µm and might allow for acquisitions close to conventional dental CBCTs. In this study, the capabilities of this new system in comparison to dental CBCTs shall be evaluated. All 8 apical osteolysis identified in CBCT were identified by both readers in all three PCCT scan protocols.

View Article and Find Full Text PDF

Different cone beam computed tomography (CBCT) protocols have shown promising results for imaging furcation defects. This study evaluates the suitability of low-dose (LD)-CBCT for this purpose. Fifty-nine furcation defects of nine upper and 16 lower molars in six human cadavers were measured by a high-dose (HD)-CBCT protocol, a LD-CBCT protocol, and a surgical protocol.

View Article and Find Full Text PDF

Background: The aim of the current study was to comparatively assess the efficiency of three different adjunctive therapy options (cold atmospheric plasma, [CAP], photodynamic therapy [PDT] and chemical decontamination via 35% phosphoric acid gel [PAG]) on decontamination of titanium implant surfaces in-vitro.

Materials And Methods: Implants were inserted in concavities of four mm in depth mimicking a bone defect at the implant recipient site. In each model, two implants were inserted in the fourth and one implant in the third quadrants.

View Article and Find Full Text PDF
Article Synopsis
  • This study evaluates the accuracy of low-dose cone beam computed tomography (LD-CBCT) in measuring buccal bone around human mandibular anterior teeth, finding it to be effective for periodontal and orthodontic treatment planning.
  • Measurements were taken from four human cadavers using both high-dose and low-dose CBCT protocols, and these were compared to reference data from probes and microscopy to gauge precision.
  • Results indicated that LD-CBCT produced measurements consistent with the reference methods, suggesting its reliability and potential clinical application for imaging buccal bone structures in dental settings.
View Article and Find Full Text PDF

Background: Induced tooth movement during orthodontic therapy requires mechano-induced bone remodeling. Besides various cytokines and growth-factors, neuronal guidance molecules gained attention for their roles in bone homeostasis and thus, potential roles during tooth movement. Several neuronal guidance molecules have been implicated in the regulation of bone remodeling.

View Article and Find Full Text PDF

Objectives: New CBCT devices have been developed which can provide "low-dose CBCTs (LD-CBCT)". Aim of this study is to investigate the suitability of LD-CBCT for measurement of alveolar buccal/oral bone.

Methods And Materials: Vestibular and oral bone loss of the teeth of seven porcine mandibles free of soft tissues were investigated by Micro-CT and three CBCT-modes: high-dose (HD), standard-dose (SD) and low-dose (LD).

View Article and Find Full Text PDF

Objectives: Evaluating structural changes in oral epithelium can assist with the diagnosis of cancerous lesions. Two-dimensional (2D) non-invasive optical coherence tomography (OCT) is an established technique for this purpose. The objective of this study was to develop and test the diagnostic accuracy of a three-dimensional (3D) evaluation method.

View Article and Find Full Text PDF

Objectives: To evaluate the diagnostic accuracy of optical coherence tomography (OCT) for the non-invasive detection of caries adjacent to ceramic materials.

Methods: Disks made from five ceramic materials (hybrid ceramic, feldspathic ceramic, zirconia-reinforced lithium silicate, lithium disilicate, and high-translucent zirconia) were ground to the recommended material thickness for single crown restorations and laminated with a 100 μm thick layer of one of three adhesive cements. The disks were fixed to extracted human molars with or without carious lesions of one of three standardized sizes.

View Article and Find Full Text PDF

Objectives: The aim of this single-center randomized controlled trial (NCT03753256) was to assess orthodontic surface sealant layer thickness and integrity in vivo during a 12-month follow-up by optical coherence tomography (OCT).

Materials And Methods: Using a split-mouth design, quadrants of 20 patients treated with fixed orthodontic appliances were included. Quadrants were randomly assigned to the sealants Pro Seal® (PS) or Opal® Seal™ (OS).

View Article and Find Full Text PDF

Objectives: Magnetic resonance imaging (MRI) image quality can be severely impaired by artifacts caused by fixed orthodontic retainers. In clinical practice, there is a trend towards using computer-aided design/computer-aided manufacturing (CAD/CAM) retainers. This study aimed to quantify MRI artifacts produced by these novel CAD/CAM retainers.

View Article and Find Full Text PDF

Purpose: Surface sealants are widely used as a prevention strategy and are indicated for young patients with insufficient oral hygiene who also need plaque removal by professional tooth cleaning. The aim of this study was to evaluate discoloration of surface sealants by plaque disclosing solutions and to test to what extent this discoloration can be reduced again by professional tooth cleaning.

Methods: In all, 96 extracted lesion-free human teeth were randomly assigned to treatment with either Pro Seal® (PS; Opal Orthodontics, South Jordan, UT, USA) or Opal®Seal™ (OS; Reliance Orthodontic Products, Itasca, IL, USA).

View Article and Find Full Text PDF

Objectives: Bilateral sagittal split osteotomy (BSSO) is a common surgical procedure to correct dentofacial deformities that involve the mandible. Usually bicortical bone fixation screw or miniplates with monocortical bone fixation screw were used to gain stability after BSSO. On the other hand, the use of resorbable screw materials had been reported.

View Article and Find Full Text PDF

Background And Objective: The aim of this single-centre, two-arm, parallel-group, double-blinded, randomised controlled trial was to investigate the disputed specific effectiveness of acupuncture by comparing acupuncture on specific and non-specific points among patients with non-chronic, painful TMDs.

Methods: Following predefined eligibility criteria, 49 consecutive patients of both sexes were recruited to the study. All subjects were diagnosed with a non-chronic (Graded Chronic Pain Scale grade <3) painful TMD, as assessed using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD).

View Article and Find Full Text PDF

Objectives: Demineralizations such as white spot lesions are among the most prevalent side effects during orthodontic treatment. Fluorescence devices, including quantitative light-induced fluorescence (QLF), exploiting the intrinsic fluorescence of enamel and teeth and most recently optical coherence tomography (OCT) were introduced for early demineralization detection. In addition to near-infrared OCT scanning, multicolor modules allow for imaging with different laser wavelengths and the detection of reflective- and fluorescent light.

View Article and Find Full Text PDF

Background: The integrity of orthodontic surface sealants after professional tooth cleaning (PTC) has previously only been evaluated in vitro. Recently, we have shown that optical coherence tomography (OCT) can successfully be used for the longitudinal assessments of sealant thickness in vitro and in vivo.

Objectives: Thus, the aim of the present study was to assess the sealant thickness after PTC in vitro and in vivo by OCT.

View Article and Find Full Text PDF

Purpose: Surface sealants are widely used in orthodontic practice to avoid enamel decalcifications in patients treated with fixed orthodontic appliances. While their clinical benefit was tested in several studies, their biocompatibility has been evaluated to a lesser extent. Therefore, the aim of this randomized prospective study was to evaluate possible adverse biological effects of three commonly used surface sealants and a bonding primer on gingival tissues by analysing cytokines in crevicular fluid of orthodontic patients after the application of surface sealants.

View Article and Find Full Text PDF

Objective: To assess surface discoloration of four enamel sealants based on different chemical compositions after exposure to artificial aging and staining solutions. Furthermore, their cleanability after polishing will be evaluated.

Materials And Methods: Selected sealants were a composite resin-based sealant with fillers (Pro Seal), a composite resin-based sealant without fillers (Light BondSealant), a resin-modified glass ionomer-based sealant (ClinproXT Varnish) and a silicon-based sealant (Protecto).

View Article and Find Full Text PDF

Objective: Optical coherence tomography (OCT) is a clinical standard in ophthalmology. Currently, its application in dentistry is gaining increasing interest. In this study, we tested the possibility to use a modified commercially available spectral domain OCT (SD-OCT) to assess the layer thickness of orthodontic surface sealants.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessioncnle6kigqlrb3rdbvnrunc8b3u3i962q): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once