Publications by authors named "Sinan Hu"
The accumulation of senescent cells is an important factor in the complex progression of aging, with significant implications for the development of numerous diseases. Thus, understanding the fundamental mechanisms of senescence is paramount for advancing preventive and therapeutic approaches to age-related conditions. Important to this pursuit is the precise identification and examination of senescent cells, contingent upon the recognition of specific biomarkers.
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- Osteoclast differentiation is crucial for bone resorption and involves the fusion of osteoclasts and their precursors.
- Osteoprotegerin (OPG) inhibits this differentiation and fusion by affecting specific molecular markers and subcellular localization in osteoclasts and precursors.
- ATP can counteract OPG's inhibitory effects, indicating a potential regulatory pathway that could be targeted for therapies related to bone metabolism.
Anti-Aging of the Nervous System and Related Neurodegenerative Diseases With Chinese Herbal Medicine.
Am J Alzheimers Dis Other Demen
November 2023
Human beings have always pursued a prolonged lifespan, while the aging of the nervous system is associated with a large variety of diseases. Pathological aging of the nervous system results in a series of neurodegenerative diseases and can cause disability and death in the elderly. Therefore, there is an urgent need for the prevention and treatment of nervous system aging.
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