Publications by authors named "Sinan Dagdelen"

The aim of this study was to investigate the possible relationship between worse clinical outcomes and the use of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) in hospitalized COVID-19 patients. A total of 247 adult patients (154 males, 93 females; mean age: 51.3 ± 14.

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Background/aim: The aim of the current study was to assess the accuracy of cardiac output (CO) measurements obtained by the Nexfin finger cuff method as compared with the FloTrac/Vigileo and echocardiography methods in coronary artery bypass grafting (CABG) patients.

Materials And Methods: First-time elective CABG patients were prospectively enrolled in this study and divided into three groups according to CO measurement method. CO measurements were performed simultaneously by three different contributors and were collected by the fourth one 24 h postoperative in the intensive care unit (ICU).

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Introduction: In this study, we investigated the association between -786T/C polymorphism of the endothelial nitric oxide (NOS3) gene in which thymidine is replaced by a cytosine at nucleotide -786 (rs 2070744) and coronary collateral circulation (CCC) in patients with stable coronary artery disease.

Materials And Methods: 286 patients having a critical stenosis (> 95%) in at least one major epicardial coronary vessel were included in the study. CCC was defined according to the Rentrop classification (R).

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Bicuspid aortic valve (BAV) is currently considered an exclusion criterion for transcatheter aortic valve implantation (TAVI). The risk of adverse aortic events such as incomplete sealing, severe paravalvular regurgitation or dislocation due to elliptic shape and asymmetric calcifications in annulus are higher in TAVI. In this case report, we detailed a case of successful trans-femoral TAVI in a 51-year old male with BAV and its management without in-hospital and 30-day complications.

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  • The study investigates the effectiveness and safety of low-dose (2,500 U) versus high-dose (5,000 U) heparin during transradial coronary angiography to reduce radial artery occlusion.
  • At day 7, radial artery occlusion rates were similar between both groups (5.9% LD vs 5.4% HD), indicating no significant difference in efficacy (p = 0.83).
  • However, the low-dose group experienced significantly less bleeding during band deflation (6.4% vs 18.3%, p < 0.001), suggesting that lower heparin doses minimize bleeding risks without compromising artery patency.
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  • - Evidence indicates that low levels of vitamin D (25-OH vitamin D) might elevate the risk of various cardiovascular diseases, including hypertension and heart failure.
  • - A study examined the relationship between vitamin D levels and coronary atherosclerosis, finding that individuals with atherosclerosis had significantly lower vitamin D levels compared to healthy controls.
  • - While low vitamin D levels were linked to increased plaque burden in coronary atherosclerosis, no significant correlation was found between vitamin D levels and the structure or morphology of the plaques.
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Background: QRS duration is an important risk factor for both sudden cardiac death and all-cause mortality in patients with moderate to severe left ventricular systolic dysfunction. However, it is unknown whether baseline QRS duration can help predict the mortality benefit from implantable cardioverter-defibrillators (ICDs) when used for primary prevention purposes.

Objective: Our objective was to examine the relationship between baseline QRS duration and mortality reduction with ICDs implanted for primary prevention by performing a meta-analysis of all available randomized clinical trials.

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Behçet's disease is a multisystemic, chronic inflammatory disorder with diffuse clinical manifestations including the cardiovascular system. Endomyocardial fibrosis is a rarely seen complication of Behçet's disease leading to progressive heart failure. We report a case of right ventricular endomyocardial fibrosis mimicking Ebstein anomaly in a 26-year-old male Turkish patient with Behçet's disease, who had heart failure symptoms.

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  • Recent trials comparing PCI and CABG for multivessel disease have been underpowered to detect mortality differences, leading to uncertainty about their long-term effects.
  • A meta-analysis of 6 randomized trials with over 6055 patients showed that CABG significantly reduces total mortality, myocardial infarction, and the need for repeat revascularization compared to PCI.
  • Although there's a non-significant trend indicating a higher risk of strokes with CABG, the evidence suggests CABG may be a better long-term option for patients with multivessel disease.
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Introduction: In selected cases with thoracic aortic aneurysm (TAA), thoracic endovascular aortic replacement (TEVAR) is commonly used and shall be proper therapy method. We are presenting a case of TAA previously treated twice by endovascular aortic approaches and complicated by type 1 endoleak.

Case: A 67-year-old male patient was admitted to our clinic with back pain at rest.

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Background: Radial artery occlusion (RAO) is an infrequent complication of transradial coronary procedures (TRA). To our knowledge, there is no satisfactory data regarding the late term incidence and predictors of RAO in the literature. Our aim was to establish the long-term incidence of radial artery occlusion and investigate its predictors.

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  • A 73-year-old female underwent transradial coronary angiography due to stable angina and myocardial ischemia signs.
  • Despite initial challenges advancing a guidewire, radial angiography revealed a perforation in the radial artery with significant contrast leakage.
  • The perforation was successfully treated with a simple external compression technique, allowing for proper healing and normal blood flow, leading to the patient’s discharge without complications.
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Transcatheter aortic valve implantation (TAVI) is now considered a viable alternative therapy to surgery in patients with severe symptomatic aortic stenosis, considered to have a high risk for surgery. Herein, we present a case of severe aortic stenosis treated with transfemoral aortic valve implantation and complicated by complete atrioventrciular block and left main coronary artery obstruction that was successfully managed with permanent pacemaker implantation and left main coronary artery stenting. Although less invasive, TAVI can be associated with major complications.

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  • The study aimed to determine how often radial artery spasm (RAS) occurs and what factors predict it during the start of a transradial approach (TRA) for coronary procedures.
  • Out of 1,722 patients, RAS occurred in 10.3% of cases, with lower procedural success rates and a higher presence of spasm among older patients and females compared to their counterparts.
  • Female gender was identified as the only independent predictor of RAS, indicating that women may be more susceptible to this complication during TRA procedures.
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Coronary artery aneurysms are localized dilatations greater than 1.5 times the diameter of the adjacent segments. These rarely seen abnormalities may lead to serious life-threatening complications such as myocardial infarction, coronary perforation and death.

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Objectives: Our aim was to establish the frequency of arterial anatomic variations and its relation to coronary procedural outcome in patients undergoing a first transradial coronary procedure.

Methods: This was a single center prospective study. A total of 1,446 consecutive patients undergoing their first transradial coronary procedure were recruited.

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Article Synopsis
  • Acute aortic dissection can lead to serious organ damage, and the best treatment for type-B aortic dissection is still debated.
  • Surgery is risky and often results in high complications, but endovascular treatments are gaining traction as a viable option.
  • This case highlights the successful teamwork between a cardiologist and a cardiovascular surgeon who used a hybrid approach to treat a patient with renal issues from acute type-B dissection.
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Objectives: Our aim was to compare the effectiveness between right radial approach (RRA) and left radial approach (LRA) by means of a randomized study in a large unselected patient population undergoing diagnostic coronary angiography.

Methods: Totally, 1,000 patients were randomized to undergo to RRA (n = 500) or LRA (n = 500). Procedure success was defined as coronary angiography completed with the initial radial artery approach without changing to another route.

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Central venous thrombosis is an important complication of venous catheterization. We presented a 49-year-old male patient who developed massive central venous thrombosis causing superior vena cava (SVC) syndrome after placement of a right subclavian vein port catheter. The patient had inoperable gastric cancer for which he had been receiving chemotherapy for two years.

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