Publications by authors named "Sinan Cao"
Article Synopsis
- - The study aimed to explore how certain immune system markers before surgery relate to the chances of esophageal squamous cell carcinoma (ESCC) returning within three years after patients undergo immunotherapy and chemotherapy.
- - Researchers analyzed 348 ESCC patients, comparing those who experienced recurrence to those who did not, looking at various immunological factors and lifestyle choices that could impact recurrence risk.
- - Key findings indicated that higher levels of CD8+ and Perforin+ cells were linked to a lower recurrence risk, while certain proteins (like EGFR and PD-L1) correlated with a higher risk; a predictive model showed high accuracy for assessing recurrence based on these markers.
Dysfunctional mitochondria producing excessive ROS are the main factors that cause ovarian aging. deficiency causes mitochondrial dysfunction and excessive ROS production, leading to ovarian aging, which is attributed to granulosa cell senescence. The pathway controlling mitochondrial proteostasis and mitochondrial homeostasis of the UPR and mitophagy are closely related with the ROS and cell senescence.
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