Publications by authors named "Sina Soleimani"

Article Synopsis
  • A study was conducted to evaluate the effects of aspirin on bleeding during arteriovenous fistula (AVF) placement surgery in end-stage renal disease patients, particularly addressing whether discontinuing aspirin is necessary before the surgery.
  • The research involved 60 patients, split evenly between those who took 80 mg of aspirin daily and those who did not, with outcomes focusing on blood loss and AVF success.
  • Results showed no significant differences in bleeding, operation duration, or AVF outcomes between the two groups, suggesting that patients can continue aspirin use without adverse effects during the surgery, while further research is encouraged.
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Bovine viral diarrhoea virus (BVDV) infection is a worldwide distributed animal disease. BVDV is the causal agent of congenital defects, diarrhea, reproductive failure, and contaminating biological products. Virus Neutralization test (VNT) as a gold standard method is used for detection of BVDV.

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Immunization with DNA vaccines as a novel alternative to conventional vaccination strategy requires adjuvant for improving vaccine efficacy. The conserved immunogenic HA2 subunit, which harbors neutralizing epitopes is a promising vaccine candidate against influenza viruses. In this study, for the first time we explore the idea of using host interferon inducible Mx protein to increase the immunogenicity of HA2 H9N2 influenza DNA vaccine.

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Purpose: The direct transmission of avian influenza viruses to human and increasing drug resisted strains posing new threats for public health. Therefore, development of efficient vaccines is needed to generate protective and persistent immunity to the viruses.

Methods: Three motifs of Mx protein sequence in human, mouse and poultry located in interferon induced (GTP ase) domain were candidate as biologic adjuvant for enhancing the immune responses against influenza virus.

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