Publications by authors named "Sina Klopfleisch"
Article Synopsis
- NOD2 is a receptor that recognizes bacterial components and is linked to an increased risk of Crohn disease due to genetic variants.
- The study analyzed protein expression changes in human cells with normal (NOD2(WT)) and disease-associated (NOD2(SNP13)) variants after stimulation with muramyl dipeptide (MDP).
- Results showed distinct protein responses, highlighting a pro-inflammatory program regulated by NOD2(WT) and suggesting potential proteomic markers for understanding chronic inflammatory bowel disease.
