Publications by authors named "Sina Delazar"

Objectives: Endometriosis is a significant cause of chronic abdominal pain and infertility in females, often overlooked due to its resemblance to other abdominopelvic pathologies. This study aims to compare the diagnostic performance and agreement rate between an abbreviated MRI protocol (aMRI) and a full MRI protocol (fMRI) for detecting pelvic endometriosis.

Methods: We retrospectively analyzed 446 consecutive MRI exams, including both full (fMRI) and abbreviated (aMRI) protocols, performed for suspected pelvic endometriosis.

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  • Developmental dysplasia of the hip (DDH) is a condition with various structural abnormalities in the hip, where early diagnosis and treatment are crucial for optimal outcomes.
  • This study involved 399 infants to assess the prevalence of DDH, particularly focusing on those with and without associated risk factors, as well as the effectiveness of ultrasound screening in diagnosing this condition.
  • Results showed that 25.8% of infants with risk factors had DDH compared to 2.8% without, with factors like being female and having limb anomalies significantly increasing the risk, highlighting ultrasound's effectiveness for early screening.
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  • The study aimed to evaluate how effective MRI-apparent diffusion coefficient (ADC) maps and radiomics were in distinguishing between liver tumors, specifically hepatocellular adenoma (HCA) and hepatocellular carcinoma (HCC).
  • A total of 55 patients were analyzed using texture features from ADC MRI images, and four different classification models were tested to see which one could best differentiate between HCA and HCC.
  • The k-nearest neighbor (KNN) classifier achieved the highest accuracy and precision in distinguishing the two types of tumors, making ADC maps a promising tool for better diagnosis compared to traditional methods.
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Giant cell tumor (GCT) is typically a benign tumor of the skeletal system that mainly presents with bone pain. Pulmonary metastasis is one of the distant presentations of GCT in patients who have previously undergone surgical resection of the tumor. Among the various presentations of pulmonary metastasis in GCT, lesions with arteriovenous malformation (AVM) features are rare and have only been reported in a few cases.

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Purpose: The current study aimed to evaluate the efficiency of dynamic contrast-enhanced (DCE) MRI visual features in classifying benign liver nodules and hepatocellular carcinoma (HCC) using a machine learning model.

Methods: 115 LI-RADS3, 137 LI-RADS4, and 140 LI-RADS5 nodules were included (392 nodules from 245 patients), which were evaluated by follow-up imaging for LR-3 and pathology results for LR-4 and LR-5 nodules. Data was collected retrospectively from 3 T and 1.

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Background And Aims: Data mining methods are effective and well-known tools for developing predictive models and extracting useful information from various data of patients. The present study aimed to predict the severity of patients with COVID-19 by applying the rule mining method using characteristics of medical images.

Methods: This retrospective study has analyzed the radiological data from 104 COVID-19 hospitalized patients diagnosed with COVID-19 in a hospital in Iran.

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Background: The huge burden of breast cancer (BC) necessitates the profound and accurate knowledge of the most recent cancer epidemiology and quality of care provided. We aimed to evaluate BC epidemiology and quality of care and examine the effects of socioeconomic development and healthcare expenditure on disparities in BC care.

Methods: The results from the GLOBOCAN 2020 study were utilized to extract data on female BC, including incidence and mortality numbers, crude rates, and age-standardized rates [age-standardized incidence rates (ASIRs) and age-standardized mortality rates (ASMRs)].

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Background: Endometrial cancer (EC) is the eighth most prevalent cancer globally. T2-weighted magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) help anatomical localization and local staging of lesions. The present study was performed to assess the diagnostic value of the simultaneous use of T2 and DWI techniques in EC evaluation.

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Background: Knowledge of normal facial vascular variations could prevent catastrophic complications of cosmetic procedures as well as providing a guide for surgical planning. Color Doppler ultrasound is a safe and noninvasive method for real time vascular evaluation.

Objective: The aim of this study was to evaluate the normal variations of the facial, angular, transverse facial, supratrochlear and supraorbital arteries in a sample of normal individuals.

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  • The study focuses on the challenges of diagnosing ultrasound-detected breast lesions that appear benign, particularly in women with dense breast tissue.
  • It compares the effectiveness of two imaging modalities, MRI and ultrasound, in accurately diagnosing these lesions, using a sample of patients including those undergoing assisted reproductive therapy and those with prior high-risk lesions.
  • Results indicated a high level of agreement between MRI and ultrasound in identifying BIRADS-3 lesions, with MRI also detecting some lesions that ultrasound missed, suggesting MRI may reduce the need for intense follow-up in certain cases.
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The growing incidence of colorectal cancer around the world highlights the significance of tumor recurrence and patient survival as 2 key elements of patient therapy. We aimed to study the factors linked with disease recurrence and survival in colon cancer. Patients with colon cancer who underwent tumor excision as their primary treatment were enrolled in this prospective cohort and monitored for 10 years.

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Background: The Radiologic Society of North America (RSNA) divides patients into four sections: negative, atypical, indeterminate, and typical coronavirus disease 2019 (COVID-19) pneumonia based on their computed tomography (CT) scan findings. Herein, we evaluate the frequency of the chest CT-scan appearances of COVID-19 according to each RSNA categorical group.

Methods: A total of 90 patients with real-time reverse transcriptase-polymerase chain reaction (RT-PCR)-confirmed COVID-19 were enrolled in this study and differences in age, sex, cardiac characteristics, and imaging features of lung parenchyma were evaluated in different categories of RSNA classification.

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Background: Ectopic intrathyroidal thymic tissue is a rare diagnosis, specifically in adults. Such ectopic tissue is usually misdiagnosed as benign or malignant thyroid lesions and is mainly investigated by ultrasonography and pathologic examination.

Case Presentation: We present the case of an adult 31-year-old Persian female patient with a cervical mass and no other significant medical history.

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Cancer can be caused by various factors, including the malfunction of tumor suppressor genes and the hyper-activation of proto-oncogenes. Tumor-associated extrachromosomal circular DNA (eccDNA) has been shown to adversely affect human health and accelerate malignant actions. Whole-genome sequencing (WGS) on different cancer types suggested that the amplification of ecDNA has increased the oncogene copy number in various cancers.

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Colorectal cancer (CRC) is a universal heterogeneous disease that is characterized by genetic and epigenetic alterations. Immunotherapy using monoclonal antibodies (mAb) and cancer vaccines are substitute strategies for CRC treatment. When cancer immunotherapy is combined with chemotherapy, surgery, and radiotherapy, the CRC treatment would become excessively efficient.

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Chloroquine has long been used for the treatment of malaria and rheumatological disorders. Accumulating evidence suggests potential use of chloroquine as a neuroprotective agent. Several studies have reported that endogenous opioids and nitric oxide (NO) system mediate the chloroquine effects.

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