Publications by authors named "Sina Azadikhah"
Article Synopsis
- - The study aimed to compare clinical and paraclinical similarities between trauma patients who tested positive (PCR+ve) for COVID-19 and those who tested negative (PCR-ve) using a case-control format.
- - Results showed that while the PCR+ve group exhibited lower lymphocyte counts, CPK, and CRP levels, these differences were not significant when analyzed further, and both groups shared similar clinical findings and comorbidities.
- - The PCR+ve group had a higher risk of mortality (OR=2.88), indicating they are more likely to experience severe outcomes, leading researchers to suggest a larger study should be conducted to better understand these differences.
Background: Management of anticoagulant therapy in COVID-19 patients is critical. Low-molecular-weight heparin (LMWH) thromboprophylaxis is already recommended, and anti-Factor Xa (anti-FXa) monitoring has been used to titrate LMWH doses.
Methods: Through a cross-sectional study, we evaluated anti-FXa activity in patients admitted to the ICU, receiving intermediate dose (30, 40, 50 mg, subcutaneously [SC], twice daily) or therapeutic dose (1 mg/kg, SC, Q12h) of enoxaparin to find whether the patients in these two groups achieved anti-FXa levels in the accepted thromboprophylaxis range.