Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury.

Study Objective: We investigate the efficacy and safety of oral paracetamol compared with oral nonsteroidal antiinflammatory drugs or combination therapy in relieving pain after blunt limb injury in an emergency department (ED).

Methods: This was a double-blind, randomized, controlled study in an ED of a university hospital in the New Territories of Hong Kong. Three hundred adult patients with painful isolated limb injuries were enrolled.